U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

srek1 splicing regulatory glutamine/lysine-rich protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 445219, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
srek1provided by ZNC
Official Full Name
splicing regulatory glutamine/lysine-rich protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-132
See related
Ensembl:ENSDARG00000009764 AllianceGenome:ZFIN:ZDB-GENE-040801-132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100974
Summary
Predicted to enable RNA binding activity. Predicted to act upstream of or within RNA splicing. Predicted to be active in nucleoplasm. Orthologous to human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See srek1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (55160240..55201187, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (54536570..54578358, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene microtubule associated serine/threonine kinase family member 4 Neighboring gene uncharacterized LOC103911124 Neighboring gene interleukin-6 receptor subunit beta-like Neighboring gene transmembrane channel-like 2a Neighboring gene proprotein convertase subtilisin/kexin type 5a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
splicing regulatory glutamine/lysine-rich protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003613.2 → NP_001003613.2  splicing regulatory glutamine/lysine-rich protein 1

    Status: VALIDATED

    Source sequence(s)
    BX950207, EH454239
    UniProtKB/TrEMBL
    A0A8M1N1N7, A2BIN4
    Related
    ENSDARP00000113861.1, ENSDART00000134937.2
    Conserved Domains (3) summary
    COG0724
    Location:170 → 248
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12260
    Location:167 → 252
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins
    cd12519
    Location:9 → 88
    RRM1_SREK1; RNA recognition motif 1 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    55160240..55201187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476086.1 → XP_021331761.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q8F0
    Conserved Domains (2) summary
    cd12260
    Location:167 → 252
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins
    cd12519
    Location:9 → 88
    RRM1_SREK1; RNA recognition motif 1 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  2. XM_005165655.4 → XP_005165712.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BCX1
    Conserved Domains (3) summary
    COG0724
    Location:170 → 248
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12260
    Location:167 → 252
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins
    cd12519
    Location:9 → 88
    RRM1_SREK1; RNA recognition motif 1 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  3. XM_017356064.2 → XP_017211553.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z6A9
    Conserved Domains (1) summary
    cd12260
    Location:90 → 175
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  4. XM_017356065.2 → XP_017211554.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z6A9
    Conserved Domains (1) summary
    cd12260
    Location:90 → 175
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  5. XM_005165658.4 → XP_005165715.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X3

    See identical proteins and their annotated locations for XP_005165715.1

    UniProtKB/TrEMBL
    A0A8M6Z6A9
    Conserved Domains (1) summary
    cd12260
    Location:90 → 175
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  6. XM_017356066.2 → XP_017211555.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z6A9
    Conserved Domains (1) summary
    cd12260
    Location:90 → 175
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

  7. XM_021476087.1 → XP_021331762.1  splicing regulatory glutamine/lysine-rich protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z6A9
    Conserved Domains (1) summary
    cd12260
    Location:90 → 175
    RRM2_SREK1; RNA recognition motif 2 in splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394612.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    23662..63383 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous