U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ndufa3 NADH:ubiquinone oxidoreductase subunit A3 [ Danio rerio (zebrafish) ]

Gene ID: 445122, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
ndufa3provided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit A3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040801-18
See related
Ensembl:ENSDARG00000041400 AllianceGenome:ZFIN:ZDB-GENE-040801-18
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:100908
Summary
Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human NDUFA3 (NADH:ubiquinone oxidoreductase subunit A3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 16
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (5717761..5721383, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (5818135..5821757, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:dkey-283b15.2 Neighboring gene zgc:158689 Neighboring gene cholecystokinin a Neighboring gene trafficking protein, kinesin binding 1a

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Hepatotoxicity assessment of Rhizoma Paridis in adult zebrafish through proteomes and metabolome. Jia Z, et al. Biomed Pharmacother, 2020 Jan. PMID 31766101
  2. Aclonifen causes developmental abnormalities in zebrafish embryos through mitochondrial dysfunction and oxidative stress. Lee JY, et al. Sci Total Environ, 2021 Jun 1. PMID 33548715
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex I IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in respirasome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Names
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
NP_001003516.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003516.3 → NP_001003516.2  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

    Status: VALIDATED

    Source sequence(s)
    CU302315, EH546667
    UniProtKB/TrEMBL
    A0A8M1N1B6
    Related
    ENSDARP00000119521.1, ENSDART00000136655.2
    Conserved Domains (1) summary
    pfam14987
    Location:2 → 83
    NADHdh_A3; NADH dehydrogenase 1 alpha subcomplex subunit 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    5717761..5721383 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous