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HMGA1 high mobility group AT-hook 1 [ Canis lupus familiaris (dog) ]

Gene ID: 442946, updated on 5-Mar-2024

Summary

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Official Symbol
HMGA1provided by VGNC
Official Full Name
high mobility group AT-hook 1provided by VGNC
Primary source
VGNC:VGNC:41709
See related
Ensembl:ENSCAFG00845026595
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
HMGIY; HMGA1A
Orthologs
human mouse all
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Genomic context

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See HMGA1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
7
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 12 NC_051816.1 (3865251..3874712)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 12 NC_006594.4 (3544725..3554094)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 12 NC_049233.1 (3707513..3716880)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 12 NC_049272.1 (3527697..3537024)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 12 NC_049753.1 (3609068..3618412)

Chromosome 12 - NC_051816.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559595 Neighboring gene glutamate metabotropic receptor 4 Neighboring gene U6 spliceosomal RNA Neighboring gene small integral membrane protein 29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene. Beuing C, et al. BMC Genet, 2008 Jul 23. PMID 18651940, Free PMC Article
  2. Expression of the high mobility group A1 (HMGA1) and A2 (HMGA2) genes in canine lymphoma: analysis of 23 cases and comparison to control cases. Joetzke AE, et al. Vet Comp Oncol, 2010 Jun. PMID 20579321
  3. The canine HMGA1. Murua Escobar H, et al. Gene, 2004 Apr 14. PMID 15087128

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. expressed significantly higher in dogs with lymphoma compared to control cases
    Title: Expression of the high mobility group A1 (HMGA1) and A2 (HMGA2) genes in canine lymphoma: analysis of 23 cases and comparison to control cases.
  2. HMGA1 gene has been assigned to canine chromosome 12q11, and consists of of 7 exons and 6 introns spanning in total 9524 bp.
    Title: Genomic characterisation, chromosomal assignment and in vivo localisation of the canine high mobility group A1 (HMGA1) gene.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high mobility group protein HMG-I/HMG-Y
Names
HMG-I(Y)
high mobility group AT-hook protein 1
high mobility group HMGA1A
high mobility group HMGA1B
high mobility group protein 1A
high mobility group protein A1
non-histone protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003387.1 → NP_001003387.1  high mobility group protein HMG-I/HMG-Y

    See identical proteins and their annotated locations for NP_001003387.1

    Status: PROVISIONAL

    Source sequence(s)
    AY366390
    UniProtKB/Swiss-Prot
    Q6URC2
    UniProtKB/TrEMBL
    A0A8C0K0G1, Q2TUW3

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051816.1 Reference ROS_Cfam_1.0

    Range
    3865251..3874712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682696.1 → XP_038538624.1  high mobility group protein HMG-I/HMG-Y isoform X1

    UniProtKB/TrEMBL
    Q6UQF0, Q6UQF9
    Related
    ENSCAFP00845036824.1, ENSCAFT00845046941.1

  2. XM_038682697.1 → XP_038538625.1  high mobility group protein HMG-I/HMG-Y isoform X2

    UniProtKB/Swiss-Prot
    Q6URC2
    UniProtKB/TrEMBL
    A0A8C0K0G1, Q2TUW3

  3. XM_038682695.1 → XP_038538623.1  high mobility group protein HMG-I/HMG-Y isoform X1

    UniProtKB/TrEMBL
    Q6UQF0, Q6UQF9

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049272.1 Alternate UMICH_Zoey_3.1

    Range
    3527697..3537024
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049753.1 Alternate UNSW_CanFamBas_1.0

    Range
    3609068..3618412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049233.1 Alternate UU_Cfam_GSD_1.0

    Range
    3707513..3716880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006594.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    3544725..3554094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6URC2.3 GenPept UniProtKB/Swiss-Prot:Q6URC2

Gene LinkOut

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