Cpsf160 Cleavage and polyadenylation specificity factor 160 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Cpsf160provided by FlyBase
Official Full Name: Cleavage and polyadenylation specificity factor 160provided by FlyBase
Primary source: FLYBASE:FBgn0024698
Locus tag: Dmel_CG10110
See related: AllianceGenome:FB:FBgn0024698
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.217; CG10110; cpsf; Cpsf; CPSF; CPSF-160; CPSF160; dCPSF-160; Dmel\CG10110
Summary: Enables myosin binding activity. Involved in positive regulation of autophagy. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Predicted to be active in nucleus. Is expressed in adult head. Human ortholog(s) of this gene implicated in myopia. Orthologous to human CPSF1 (cleavage and polyadenylation specific factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (14497347..14503488, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (10384852..10390993, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables myosin binding	IPI Inferred from Physical Interaction more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of autophagy	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mRNA cleavage and polyadenylation specificity factor complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

Names: CG10110-PA; CG10110-PB; Cpsf160-PA; Cpsf160-PB; cleavage and polyadenylation specificity factor; drosophila cleavage and polyadenylation stimulation factor-160

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The following sections contain reference sequences that belong to a specific genome build. Explain