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sumo3b small ubiquitin like modifier 3b [ Danio rerio (zebrafish) ]

Gene ID: 436950, updated on 27-Mar-2024

Summary

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Official Symbol
sumo3bprovided by ZNC
Official Full Name
small ubiquitin like modifier 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-426
See related
Ensembl:ENSDARG00000035993 AllianceGenome:ZFIN:ZDB-GENE-040718-426
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sumo3; fc66f10; fl11h12; zgc:86902; wu:fc66f10; wu:fl11h12
Summary
Predicted to enable protein tag and ubiquitin-like protein ligase binding activity. Predicted to be involved in protein sumoylation. Predicted to be located in PML body and cytoplasm. Predicted to be active in nucleus. Orthologous to human SUMO3 (small ubiquitin like modifier 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (12648705..12652991, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (12677502..12681788, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene transformer 2 beta homolog Neighboring gene thrombospondin-type laminin G domain and EAR repeats b Neighboring gene PTTG1 interacting protein b Neighboring gene myosin X, like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Fish SUMO3 functions as a critical antiviral molecule against iridovirus and nodavirus. Wei J, et al. Fish Shellfish Immunol, 2019 Mar. PMID 30593901
  2. Single Cell Transcriptome Sequencing of Zebrafish Testis Revealed Novel Spermatogenesis Marker Genes and Stronger Leydig-Germ Cell Paracrine Interactions. Qian P, et al. Front Genet, 2022. PMID 35360857, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein tag activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein sumoylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small ubiquitin-related modifier 3
Names
SMT3 suppressor of mif two 3 homolog 3
SMT3 suppressor of mif two 3 homolog 3b
SUMO-3
SUMO-3-B
small ubiquitin-like modifier protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002677.2 → NP_001002677.2  small ubiquitin-related modifier 3

    Status: VALIDATED

    Source sequence(s)
    BC075786, BX511126
    UniProtKB/Swiss-Prot
    Q6DI05
    UniProtKB/TrEMBL
    F1QRX2
    Related
    ENSDARP00000052255.5, ENSDART00000052256.6
    Conserved Domains (1) summary
    cd16115
    Location:16 → 87
    Ubl_SUMO2_3_4; ubiquitin-like (Ubl) domain found in small ubiquitin-related modifier SUMO-2, SUMO-3, SUMO-4, and similar proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    12648705..12652991 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6DI05.1 GenPept UniProtKB/Swiss-Prot:Q6DI05

Gene LinkOut

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