gtf2h3 general transcription factor IIH, polypeptide 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gtf2h3provided by ZNC
Official Full Name: general transcription factor IIH, polypeptide 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-302
See related: Ensembl:ENSDARG00000067560 AllianceGenome:ZFIN:ZDB-GENE-040718-302
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc26a07; gtf2h3-2; zgc:92759; wu:fc26a07
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in nucleotide-excision repair and phosphorylation of RNA polymerase II C-terminal domain. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Orthologous to human GTF2H3 (general transcription factor IIH subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (69650148..69660907)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (68877596..68888355)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in nucleotide-excision repair	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within nucleotide-excision repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIH core complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIIH core complex	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIH holo complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: general transcription factor IIH subunit 3

Names: p34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128422.1 → NP_001121894.1 general transcription factor IIH subunit 3

Status: VALIDATED

Source sequence(s)

CT978957

UniProtKB/TrEMBL

A0A8M1NHH3, A5WWE3

Related

ENSDARP00000088015.4, ENSDART00000097244.5

Conserved Domains (1) summary

pfam03850
Location:7 → 274

Tfb4; Transcription factor Tfb4