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FES FES proto-oncogene, tyrosine kinase [ Gallus gallus (chicken) ]

Gene ID: 429374, updated on 3-Apr-2024

Summary

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Symbol
FESprovided by CGNC
Full Name
FES proto-oncogene, tyrosine kinaseprovided by CGNC
Primary source
CGNC:53636
See related
Ensembl:ENSGALG00010000049
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
c-fps
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (20122116..20127915, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (19986430..19992229, complement)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101751992 Neighboring gene mannosidase alpha class 2A member 2 Neighboring gene furin, paired basic amino acid cleaving enzyme Neighboring gene microRNA mir-12218 Neighboring gene microfibrillar associated protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequence and topography of chicken c-fps. Genesis of a retroviral oncogene encoding a tyrosine-specific protein kinase. Huang CC, et al. J Mol Biol, 1985 Jan 20. PMID 3879969
  2. Defining the borders of the chicken proto-fps gene, a precursor of Fujinami sarcoma virus. Pfaff SL, et al. Virology, 1985 Oct 30. PMID 2996222

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mast cell degranulation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Fes/Fps
Names
c-fps proto oncogene
feline sarcoma oncogene
XP_003641916.5
XP_015147644.1
XP_015147646.1
XP_015147647.1
XP_040536333.1
XP_040536334.2
XP_040536335.1
XP_040536336.1
XP_046755166.1
XP_046781127.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    20122116..20127915 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003641868.5 → XP_003641916.5  tyrosine-protein kinase Fes/Fps isoform X2

    Related
    ENSGALP00010000048.1, ENSGALT00010000072.1

  2. XM_015292160.4 → XP_015147646.1  tyrosine-protein kinase Fes/Fps isoform X2

    UniProtKB/TrEMBL
    Q90778
    Conserved Domains (4) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:455 → 539
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:566 → 817
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes
    pfam07714
    Location:565 → 816
    Pkinase_Tyr; Protein tyrosine kinase

  3. XM_015292158.4 → XP_015147644.1  tyrosine-protein kinase Fes/Fps isoform X1

    UniProtKB/TrEMBL
    A0A8V0X6E7
    Conserved Domains (4) summary
    cd07685
    Location:61 → 297
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:509 → 593
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:620 → 871
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes
    pfam07714
    Location:619 → 870
    Pkinase_Tyr; Protein tyrosine kinase

  4. XM_015292161.4 → XP_015147647.1  tyrosine-protein kinase Fes/Fps isoform X2

    UniProtKB/TrEMBL
    Q90778
    Conserved Domains (4) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:455 → 539
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:566 → 817
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes
    pfam07714
    Location:565 → 816
    Pkinase_Tyr; Protein tyrosine kinase

  5. XM_046899210.1 → XP_046755166.1  tyrosine-protein kinase Fes/Fps isoform X3

RNA

  1. XR_003076974.3 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    19986430..19992229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040680400.2 → XP_040536334.2  tyrosine-protein kinase Fes/Fps isoform X2

  2. XM_040680401.2 → XP_040536335.1  tyrosine-protein kinase Fes/Fps isoform X2

    UniProtKB/TrEMBL
    Q90778
    Conserved Domains (3) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:455 → 539
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:566 → 817
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes

  3. XM_040680399.2 → XP_040536333.1  tyrosine-protein kinase Fes/Fps isoform X1

    UniProtKB/TrEMBL
    A0A8V0X6E7
    Conserved Domains (3) summary
    cd07685
    Location:61 → 297
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:509 → 593
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:620 → 871
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes

  4. XM_040680402.2 → XP_040536336.1  tyrosine-protein kinase Fes/Fps isoform X2

    UniProtKB/TrEMBL
    Q90778
    Conserved Domains (3) summary
    cd07685
    Location:7 → 243
    F-BAR_Fes; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Fes (feline sarcoma) tyrosine kinase
    cd10361
    Location:455 → 539
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:566 → 817
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes

  5. XM_046925171.1 → XP_046781127.1  tyrosine-protein kinase Fes/Fps isoform X3

RNA

  1. XR_005853077.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001031571.1: Suppressed sequence

    Description
    NM_001031571.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
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