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PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 [ Gallus gallus (chicken) ]

Gene ID: 429096, updated on 3-Apr-2024

Summary

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Symbol
PIK3R3provided by CGNC
Full Name
phosphoinositide-3-kinase regulatory subunit 3provided by CGNC
Primary source
CGNC:7864
See related
Ensembl:ENSGALG00010023309
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

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Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (21115919..21174660, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (21124430..21183175, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121111449 Neighboring gene riboflavin binding protein Neighboring gene microtubule associated serine/threonine kinase 2 Neighboring gene uncharacterized LOC121111450 Neighboring gene tetraspanin 1 Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit gamma
Names
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    21115919..21174660 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046944862.1 → XP_046800818.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZUM5
    Related
    ENSGALP00010034553.1, ENSGALT00010056833.1

  2. XM_426652.8 → XP_426652.3  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

    UniProtKB/TrEMBL
    A0A8V1A076
    Related
    ENSGALP00010034555.1, ENSGALT00010056837.1
    Conserved Domains (5) summary
    cd09930
    Location:622 → 725
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:328 → 438
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:443 → 603
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
    cl02570
    Location:116 → 293
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl17036
    Location:7 → 79
    SH3; Src Homology 3 domain superfamily

  3. XM_046944863.1 → XP_046800819.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X4

  4. XM_004936762.5 → XP_004936819.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3

    See identical proteins and their annotated locations for XP_004936819.1

    UniProtKB/TrEMBL
    A0A8V0ZSM3
    Related
    ENSGALP00010034551.1, ENSGALT00010056829.1
    Conserved Domains (3) summary
    cd09930
    Location:352 → 455
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:58 → 168
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:173 → 333
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    21124430..21183175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046923117.1 → XP_046779073.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZUM5

  2. XM_040678458.2 → XP_040534392.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

    UniProtKB/TrEMBL
    A0A8V1A076
    Conserved Domains (5) summary
    cd09930
    Location:622 → 725
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:328 → 438
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:443 → 603
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
    cl02570
    Location:116 → 293
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl17036
    Location:7 → 79
    SH3; Src Homology 3 domain superfamily

  3. XM_046923118.1 → XP_046779074.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X4

  4. XM_040678460.2 → XP_040534394.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZSM3
    Conserved Domains (3) summary
    cd09930
    Location:352 → 455
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:58 → 168
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:173 → 333
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
Nucleotide Protein Strain
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