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PAK6 p21 (RAC1) activated kinase 6 [ Gallus gallus (chicken) ]

Gene ID: 428837, updated on 3-Apr-2024

Summary

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Symbol
PAK6provided by CGNC
Full Name
p21 (RAC1) activated kinase 6provided by CGNC
Primary source
CGNC:3583
See related
Ensembl:ENSGALG00010023257
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

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Location:
chromosome: 5
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (814999..841925)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (809613..836538)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene cadherin related family member 5 Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene phospholipase C beta 2 Neighboring gene InaF motif containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 6
Names
p21 protein (Cdc42/Rac)-activated kinase 6
p21(CDKN1A)-activated kinase 6
XP_004941346.1
XP_004941348.1
XP_015141765.1
XP_040528533.1
XP_040528534.1
XP_040528539.1
XP_040528541.1
XP_040557443.1
XP_046775036.1
XP_046798142.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    814999..841925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046942186.1 → XP_046798142.1  serine/threonine-protein kinase PAK 6 isoform X2

  2. XM_004941289.4 → XP_004941346.1  serine/threonine-protein kinase PAK 6 isoform X1

    See identical proteins and their annotated locations for XP_004941346.1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  3. XM_040701509.2 → XP_040557443.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Related
    ENSGALP00010034453.1, ENSGALT00010056711.1
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  4. XM_015286279.3 → XP_015141765.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  5. XM_004941291.5 → XP_004941348.1  serine/threonine-protein kinase PAK 6 isoform X2

    See identical proteins and their annotated locations for XP_004941348.1

    UniProtKB/TrEMBL
    A0A8V0ZM37
    Related
    ENSGALP00010034445.1, ENSGALT00010056703.1
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    809613..836538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046919080.1 → XP_046775036.1  serine/threonine-protein kinase PAK 6 isoform X2

  2. XM_040672599.2 → XP_040528533.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  3. XM_040672605.2 → XP_040528539.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  4. XM_040672600.2 → XP_040528534.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZM37, A0A8V0ZSD2
    Conserved Domains (2) summary
    cd01093
    Location:14 → 59
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:375 → 671
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  5. XM_040672607.2 → XP_040528541.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZM37
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
Nucleotide Protein Strain
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