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PIK3R4 phosphoinositide-3-kinase regulatory subunit 4 [ Gallus gallus (chicken) ]

Gene ID: 428449, updated on 3-Apr-2024

Summary

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Symbol
PIK3R4provided by CGNC
Full Name
phosphoinositide-3-kinase regulatory subunit 4provided by CGNC
Primary source
CGNC:8798
See related
Ensembl:ENSGALG00010018451
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (41503638..41526706, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (41562139..41585205, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene collagen type VI alpha 6 chain Neighboring gene uncharacterized LOC121112226 Neighboring gene ATPase secretory pathway Ca2+ transporting 1 Neighboring gene asteroid homolog 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagy of peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in late endosome to vacuole transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein targeting to vacuole IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in late endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus-vacuole junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphoinositide 3-kinase regulatory subunit 4
Names
phosphoinositide-3-kinase, regulatory subunit 4, p150
XP_001235241.1
XP_004939498.4
XP_040518768.2
XP_040518769.1
XP_046767943.1
XP_046787704.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    41503638..41526706 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931748.1 → XP_046787704.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X2

  2. XM_004939441.5 → XP_004939498.4  phosphoinositide 3-kinase regulatory subunit 4 isoform X1

    Related
    ENSGALP00010026570.1, ENSGALT00010044626.1

  3. XM_001235240.6 → XP_001235241.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YZZ0
    Related
    ENSGALP00010026567.1, ENSGALT00010044622.1
    Conserved Domains (5) summary
    smart00320
    Location:1330 → 1361
    WD40; WD40 repeats
    cd13980
    Location:25 → 319
    STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
    sd00044
    Location:538 → 565
    HEAT; HEAT repeat [structural motif]
    sd00039
    Location:1000 → 1043
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:988 → 1272
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    41562139..41585205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046911987.1 → XP_046767943.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X2

  2. XM_040662834.2 → XP_040518768.2  phosphoinositide 3-kinase regulatory subunit 4 isoform X1

  3. XM_040662835.2 → XP_040518769.1  phosphoinositide 3-kinase regulatory subunit 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YZZ0
    Conserved Domains (5) summary
    smart00320
    Location:1330 → 1361
    WD40; WD40 repeats
    cd13980
    Location:25 → 319
    STKc_Vps15; Catalytic domain of the Serine/Threonine kinase, Vacuolar protein sorting-associated protein 15
    sd00044
    Location:538 → 565
    HEAT; HEAT repeat [structural motif]
    sd00039
    Location:1000 → 1043
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:988 → 1272
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001039323.1: Suppressed sequence

    Description
    NM_001039323.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
Nucleotide Protein Strain
Heading Accession and Version

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