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HEY1 hes related family bHLH transcription factor with YRPW motif 1 [ Gallus gallus (chicken) ]

Gene ID: 428365, updated on 5-Mar-2024

Summary

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Symbol
HEY1provided by CGNC
Full Name
hes related family bHLH transcription factor with YRPW motif 1provided by CGNC
Primary source
CGNC:11739
See related
Ensembl:ENSGALG00010003330
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (120346174..120350024, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (120536871..120540699, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene SUN domain-containing protein 3-like Neighboring gene stathmin 2 Neighboring gene tumor protein D52 Neighboring gene uncharacterized LOC101750761 Neighboring gene zinc finger and BTB domain containing 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. Ménard M, et al. PLoS Biol, 2018 May. PMID 29750782, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TrkC tumor suppressor activity requires Hey1 and p53.
    Title: Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in circulatory system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hairy/enhancer-of-split related with YRPW motif protein 1
Names
hairy/enhancer-of-split related with YRPW motif 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    120346174..120350024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015282862.4 → XP_015138348.2  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XIX5
    Related
    ENSGALP00010004677.1, ENSGALT00010007789.1
    Conserved Domains (2) summary
    smart00511
    Location:160 → 206
    ORANGE; Orange domain
    cl00081
    Location:81 → 162
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_025148013.3 → XP_025003781.2  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XIX5
    Conserved Domains (2) summary
    smart00511
    Location:185 → 231
    ORANGE; Orange domain
    cl00081
    Location:81 → 187
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    120536871..120540699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040665052.2 → XP_040520986.1  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XIX5
    Conserved Domains (2) summary
    smart00511
    Location:160 → 206
    ORANGE; Orange domain
    cl00081
    Location:81 → 162
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_040665051.2 → XP_040520985.1  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XIX5
    Conserved Domains (2) summary
    smart00511
    Location:185 → 231
    ORANGE; Orange domain
    cl00081
    Location:81 → 187
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily
Nucleotide Protein
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