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CG10375 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42812, updated on 10-May-2024

Summary

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Official Symbol
CG10375provided by FlyBase
Primary source
FLYBASE:FBgn0039116
Locus tag
Dmel_CG10375
See related
AllianceGenome:FB:FBgn0039116
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10375
Summary
Predicted to be active in nucleus. Orthologous to human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
95B1-95B1; 3-80 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23767712..23768984)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19593434..19594706)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene undicht Neighboring gene Lipid storage droplet-1 Neighboring gene uncharacterized protein Neighboring gene twister Neighboring gene uncharacterized protein Neighboring gene Nucleoporin 98-96kD

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology. Raut S, et al. G3 (Bethesda), 2017 Jul 5. PMID 28500055, Free PMC Article
  2. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article
  3. Mettl3-dependent m(6)A modification attenuates the brain stress response in Drosophila. Perlegos AE, et al. Nat Commun, 2022 Sep 14. PMID 36104353, Free PMC Article
  4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
  5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10375-PA
CG10375-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    23767712..23768984
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142928.3 → NP_651185.1  uncharacterized protein Dmel_CG10375, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651185.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VCH9
    Related
    FBpp0083849
    Conserved Domains (1) summary
    cd06257
    Location:54 → 109
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...

  2. NM_001170233.1 → NP_001163704.1  uncharacterized protein Dmel_CG10375, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163704.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AVU6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0AVU6 A0AVU6
Q9VCH9 Q9VCH9

Gene LinkOut

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