HTR2A 5-hydroxytryptamine receptor 2A [Gallus gallus (chicken)] - Gene

Summary

Symbol: HTR2Aprovided by CGNC
Full Name: 5-hydroxytryptamine receptor 2Aprovided by CGNC
Primary source: CGNC:12754
See related: Ensembl:ENSGALG00010004769
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (168226174..168256918, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (168314882..168345707, complement)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Genome-wide survey and functional analysis reveal TCF21 promotes chicken preadipocyte differentiation by directly upregulating HTR2A.
Title: Genome-wide survey and functional analysis reveal TCF21 promotes chicken preadipocyte differentiation by directly upregulating HTR2A.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G protein-coupled serotonin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables neurotransmitter receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in dendrite	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5-hydroxytryptamine receptor 2A

Names: 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001318420.2 → NP_001305349.1 5-hydroxytryptamine receptor 2A

Status: VALIDATED

Source sequence(s)

HQ438965, JAENSK010000027

UniProtKB/TrEMBL

A0A8V0XKI8, E1BVI5, F5ANP1

Related

ENSGALP00010006299.1, ENSGALT00010011060.1

Conserved Domains (2) summary

pfam00001
Location:89 → 377

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:87 → 220

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

168226174..168256918 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025151250.3 → XP_025007018.1 5-hydroxytryptamine receptor 2A isoform X1

UniProtKB/TrEMBL

A0A8V0XKI8, A0A8V0XNB4

Related

ENSGALP00010006305.1, ENSGALT00010011075.1

Conserved Domains (1) summary

cd15304
Location:73 → 388

7tmA_5-HT2A; serotonin receptor subtype 2A, member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

168314882..168345707 complement

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GenBank, FASTA, Sequence Viewer (Graphics)