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GNB3 G protein subunit beta 3 [ Gallus gallus (chicken) ]

Gene ID: 427945, updated on 3-Apr-2024

Summary

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Symbol
GNB3provided by CGNC
Full Name
G protein subunit beta 3provided by CGNC
Primary source
CGNC:66543
See related
Ensembl:ENSGALG00010023351
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (77193355..77205055)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (77393592..77405290)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene CD4 molecule Neighboring gene G protein-coupled receptor 162 Neighboring gene prolyl 3-hydroxylase 3 Neighboring gene cell division cycle associated 3 Neighboring gene ubiquitin specific peptidase 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The D153del mutation in GNB3 gene causes tissue specific signalling patterns and an abnormal renal morphology in Rge chickens. Tummala H, et al. PLoS One, 2011. PMID 21887213, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These findings confirm that the D153del mutation in GNB3 gene targets GNB3 protein to early degradation.
    Title: The D153del mutation in GNB3 gene causes tissue specific signalling patterns and an abnormal renal morphology in Rge chickens.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor complex adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Names
guanine nucleotide binding protein (G protein), beta polypeptide 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001389487.2 → NP_001376416.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000015
    UniProtKB/TrEMBL
    A0A1D5P7Z5, A0A8V0ZW31
    Related
    ENSGALP00010034615.1, ENSGALT00010056927.1
    Conserved Domains (2) summary
    cd00200
    Location:48 → 340
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:58 → 95
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    77193355..77205055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701410.2 → XP_040557344.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P7Z5, A0A8V0ZW31
    Conserved Domains (2) summary
    cd00200
    Location:48 → 340
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:58 → 95
    7WD40; WD40 repeat [structural motif]

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    77393592..77405290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908568.1 → XP_046764524.1  guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5P7Z5
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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