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PDE8B phosphodiesterase 8B [ Gallus gallus (chicken) ]

Gene ID: 427645, updated on 5-Mar-2024

Summary

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Symbol
PDE8Bprovided by CGNC
Full Name
phosphodiesterase 8Bprovided by CGNC
Primary source
CGNC:3191
See related
Ensembl:ENSGALG00010010275
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (23748732..23829713, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (23748732..23829713, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene orthopedia homeobox Neighboring gene WD repeat domain 41 Neighboring gene uncharacterized LOC107051953 Neighboring gene small nucleolar RNA SNORA47 Neighboring gene angiogenic factor with G-patch and FHA domains 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
XP_004937385.2
XP_004937386.2
XP_025000690.2
XP_040512025.1
XP_040512026.1
XP_040512027.1
XP_046791589.1
XP_046791590.1
XP_046791591.1
XP_046791593.1
XP_046791594.1
XP_046791595.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    23748732..23829713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025144922.3 → XP_025000690.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5

    Conserved Domains (3) summary
    COG0745
    Location:53 → 134
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00077
    Location:516 → 711
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:183 → 275
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

  2. XM_040656091.2 → XP_040512025.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X3

    Conserved Domains (3) summary
    COG0745
    Location:54 → 135
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00077
    Location:517 → 712
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:184 → 276
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

  3. XM_004937329.5 → XP_004937386.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y8J0
    Related
    ENSGALP00010013909.1, ENSGALT00010024509.1
    Conserved Domains (3) summary
    COG0745
    Location:134 → 215
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00077
    Location:597 → 792
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:264 → 356
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

  4. XM_040656093.2 → XP_040512027.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X6

    Conserved Domains (2) summary
    cd00077
    Location:529 → 724
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:196 → 288
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

  5. XM_040656092.2 → XP_040512026.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y689
    Related
    ENSGALP00010013908.1, ENSGALT00010024505.1
    Conserved Domains (2) summary
    cd00077
    Location:578 → 773
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:245 → 337
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

  6. XM_004937328.5 → XP_004937385.2  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1

    Conserved Domains (3) summary
    COG0745
    Location:135 → 216
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
    cd00077
    Location:598 → 793
    HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    cd00130
    Location:265 → 357
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    23748732..23829713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046935638.1 → XP_046791594.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X5

  2. XM_046935635.1 → XP_046791591.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X3

  3. XM_046935634.1 → XP_046791590.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X2

    UniProtKB/TrEMBL
    A0A8V0Y8J0

  4. XM_046935639.1 → XP_046791595.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X6

  5. XM_046935637.1 → XP_046791593.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y689

  6. XM_046935633.1 → XP_046791589.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1

Nucleotide Protein
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