ADRB2 adrenoceptor beta 2 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: ADRB2provided by CGNC
Official Full Name: adrenoceptor beta 2provided by CGNC
Primary source: CGNC:66534
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (8239838..8265228, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (8245024..8270430, complement)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

noradrenaline acts at beta1-adrenergic receptors in the basal ganglia, and there are separate roles for beta2 and -3 receptors in memory processing
Title: Contrasting roles for beta1, beta2 and beta3-adrenoceptors in memory formation in the chick.

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Pathways from PubChem

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General gene information

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Markers

ADRB2sts1 (e-PCR)
- UniSTS:258478

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta2-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables norepinephrine binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: beta-2 adrenergic receptor

Names: adrenergic, beta-2-, receptor, surface

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

8239838..8265228 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015293684.4 → XP_015149170.1 beta-2 adrenergic receptor

UniProtKB/TrEMBL

A0A1D5P7A9, A0A6J3ZXV5

Conserved Domains (1) summary

cd15957
Location:31 → 330

7tmA_Beta2_AR; beta-2 adrenergic receptors (adrenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

8245024..8270430 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040683024.2 → XP_040538958.1 beta-2 adrenergic receptor

UniProtKB/TrEMBL

A0A1D5P7A9, A0A6J3ZXV5

Conserved Domains (1) summary

cd15957
Location:31 → 330

7tmA_Beta2_AR; beta-2 adrenergic receptors (adrenoceptors), member of the class A family of seven-transmembrane G protein-coupled receptors