CDC14B cell division cycle 14B [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CDC14Bprovided by CGNC
Official Full Name: cell division cycle 14Bprovided by CGNC
Primary source: CGNC:53099
See related: Ensembl:ENSGALG00010010844
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: Z

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	Z	NC_052572.1 (42822549..42872095, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	Z	NC_059536.1 (42822549..42872095, complement)

Chromosome Z - NC_052572.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein tyrosine/serine/threonine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info	PubMed
involved_in microtubule cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytokinesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of exit from mitosis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleolus	IEA Inferred from Electronic Annotation more info	PubMed
located_in spindle pole	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity protein phosphatase CDC14B

Names: CDC14 cell division cycle 14 homolog B

NP_001305334.1

EC 3.1.3.16

EC 3.1.3.48

XP_004949290.1

EC 3.1.3.16

EC 3.1.3.48

XP_004949291.1

EC 3.1.3.16

EC 3.1.3.48

XP_004949293.1

EC 3.1.3.16

EC 3.1.3.48

XP_004949294.1

EC 3.1.3.16

EC 3.1.3.48

XP_040511557.1

EC 3.1.3.16

EC 3.1.3.48

XP_040511558.1

EC 3.1.3.16

EC 3.1.3.48

XP_046761425.1

EC 3.1.3.16

EC 3.1.3.48

XP_046761426.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791280.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791281.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791282.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791283.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791284.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791285.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791286.1

EC 3.1.3.16

EC 3.1.3.48

XP_046791287.1

EC 3.1.3.16

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001318405.2 → NP_001305334.1 dual specificity protein phosphatase CDC14B

Status: PROVISIONAL

Source sequence(s)

JAENSK010000094

UniProtKB/TrEMBL

A0A8V0YF75, D5K9Y4, F1NYF9

Related

ENSGALP00010014641.1, ENSGALT00010025981.1

Conserved Domains (3) summary

COG2453
Location:213 → 367

CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]

pfam14671
Location:52 → 190

DSPn; Dual specificity protein phosphatase, N-terminal half

cl27228
Location:375 → 418

PolC_DP2; DNA polymerase II large subunit DP2

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

42822549..42872095 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_004949237.5 → XP_004949294.1 dual specificity protein phosphatase CDC14B isoform X5

UniProtKB/TrEMBL

A0A8V0YF75

Conserved Domains (3) summary

COG2453
Location:213 → 367

CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]

pfam14671
Location:54 → 189

DSPn; Dual specificity protein phosphatase, N-terminal half

cl21483
Location:247 → 361

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
XM_004949234.5 → XP_004949291.1 dual specificity protein phosphatase CDC14B isoform X2

UniProtKB/TrEMBL

A0A8V0YF75

Conserved Domains (3) summary

COG2453
Location:213 → 367

CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]

pfam14671
Location:54 → 189

DSPn; Dual specificity protein phosphatase, N-terminal half

cl21483
Location:247 → 361

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
XM_004949233.5 → XP_004949290.1 dual specificity protein phosphatase CDC14B isoform X1

UniProtKB/TrEMBL

A0A1D5PXT4, A0A8V0YF75

Related

ENSGALP00010014635.1, ENSGALT00010025974.1

Conserved Domains (3) summary

COG2453
Location:213 → 367

CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]

pfam14671
Location:52 → 190

DSPn; Dual specificity protein phosphatase, N-terminal half

cl27228
Location:375 → 418

PolC_DP2; DNA polymerase II large subunit DP2
XM_040655623.2 → XP_040511557.1 dual specificity protein phosphatase CDC14B isoform X3

UniProtKB/TrEMBL

A0A8V0Y6P9, A0A8V0YF75

Related

ENSGALP00010014618.1, ENSGALT00010025954.1

Conserved Domains (3) summary

PRK14715
Location:375 → 418

PRK14715; DNA-directed DNA polymerase II large subunit

cd14499
Location:201 → 373

CDC14_C; C-terminal dual-specificity phosphatase domain of CDC14 family proteins

cd17657
Location:52 → 191

CDC14_N; N-terminal domain pseudophosphatase domain of CDC14 family proteins
XM_004949236.5 → XP_004949293.1 dual specificity protein phosphatase CDC14B isoform X4

See identical proteins and their annotated locations for XP_004949293.1

UniProtKB/TrEMBL

A0A8V0YF75

Conserved Domains (3) summary

PRK14715
Location:375 → 418

PRK14715; DNA-directed DNA polymerase II large subunit

cd14499
Location:201 → 373

CDC14_C; C-terminal dual-specificity phosphatase domain of CDC14 family proteins

cd17657
Location:52 → 191

CDC14_N; N-terminal domain pseudophosphatase domain of CDC14 family proteins
XM_046905469.1 → XP_046761425.1 dual specificity protein phosphatase CDC14B isoform X4
XM_046905470.1 → XP_046761426.1 dual specificity protein phosphatase CDC14B isoform X6
XM_040655624.2 → XP_040511558.1 dual specificity protein phosphatase CDC14B isoform X4

UniProtKB/TrEMBL

A0A8V0YF75

Conserved Domains (3) summary

PRK14715
Location:375 → 418

PRK14715; DNA-directed DNA polymerase II large subunit

cd14499
Location:201 → 373

CDC14_C; C-terminal dual-specificity phosphatase domain of CDC14 family proteins

cd17657
Location:52 → 191

CDC14_N; N-terminal domain pseudophosphatase domain of CDC14 family proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

42822549..42872095 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046935330.1 → XP_046791286.1 dual specificity protein phosphatase CDC14B isoform X5
XM_046935325.1 → XP_046791281.1 dual specificity protein phosphatase CDC14B isoform X2
XM_046935324.1 → XP_046791280.1 dual specificity protein phosphatase CDC14B isoform X1

UniProtKB/TrEMBL

A0A1D5PXT4
XM_046935326.1 → XP_046791282.1 dual specificity protein phosphatase CDC14B isoform X3

UniProtKB/TrEMBL

A0A8V0Y6P9
XM_046935329.1 → XP_046791285.1 dual specificity protein phosphatase CDC14B isoform X4
XM_046935327.1 → XP_046791283.1 dual specificity protein phosphatase CDC14B isoform X4
XM_046935331.1 → XP_046791287.1 dual specificity protein phosphatase CDC14B isoform X6
XM_046935328.1 → XP_046791284.1 dual specificity protein phosphatase CDC14B isoform X4