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PLAT plasminogen activator, tissue type [ Gallus gallus (chicken) ]

Gene ID: 426791, updated on 3-Apr-2024

Summary

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Official Symbol
PLATprovided by CGNC
Official Full Name
plasminogen activator, tissue typeprovided by CGNC
Primary source
CGNC:2713
See related
Ensembl:ENSGALG00010017948
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 22 NC_052553.1 (2880452..2893641, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 22 NC_052594.1 (2927977..2941148, complement)

Chromosome 22 - NC_052553.1Genomic Context describing neighboring genes Neighboring gene lysine acetyltransferase 6A Neighboring gene adaptor related protein complex 3 mu 2 subunit Neighboring gene inhibitor of nuclear factor kappa B kinase subunit beta Neighboring gene voltage dependent anion channel 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in plasminogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in smooth muscle cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tissue-type plasminogen activator
XP_004947670.1
XP_024998656.1
XP_024998657.1
XP_040545367.1
XP_040545368.1
XP_040545369.1
XP_046759379.1
XP_046759380.1
XP_046759381.1
XP_046787695.1
XP_046787696.1
XP_046787697.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052553.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2880452..2893641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004947613.5 → XP_004947670.1  tissue-type plasminogen activator isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXI3, E1C209
    Related
    ENSGALP00010025786.1, ENSGALT00010043384.1
    Conserved Domains (3) summary
    cd00108
    Location:134 → 219
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:325 → 564
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:226 → 307
    Kringle; Kringle domain

  2. XM_046903423.1 → XP_046759379.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9

  3. XM_025142888.3 → XP_024998656.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9, A0A8V0YXI3
    Related
    ENSGALP00010025783.1, ENSGALT00010043380.1
    Conserved Domains (3) summary
    cd00108
    Location:125 → 210
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:316 → 555
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:217 → 298
    Kringle; Kringle domain

  4. XM_025142889.3 → XP_024998657.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9, A0A8V0YXI3
    Conserved Domains (3) summary
    cd00108
    Location:125 → 210
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:316 → 555
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:217 → 298
    Kringle; Kringle domain

  5. XM_046903424.1 → XP_046759380.1  tissue-type plasminogen activator isoform X3

  6. XM_046903425.1 → XP_046759381.1  tissue-type plasminogen activator isoform X4

    Related
    ENSGALP00010025779.1, ENSGALT00010043374.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052594.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2927977..2941148 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040689433.2 → XP_040545367.1  tissue-type plasminogen activator isoform X1

    UniProtKB/TrEMBL
    A0A8V0YXI3, E1C209
    Conserved Domains (3) summary
    cd00108
    Location:134 → 219
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:325 → 564
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:226 → 307
    Kringle; Kringle domain

  2. XM_046931739.1 → XP_046787695.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9

  3. XM_040689434.2 → XP_040545368.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9, A0A8V0YXI3
    Conserved Domains (3) summary
    cd00108
    Location:125 → 210
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:316 → 555
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:217 → 298
    Kringle; Kringle domain

  4. XM_040689435.2 → XP_040545369.1  tissue-type plasminogen activator isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ULJ9, A0A8V0YXI3
    Conserved Domains (3) summary
    cd00108
    Location:125 → 210
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd00190
    Location:316 → 555
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00051
    Location:217 → 298
    Kringle; Kringle domain

  5. XM_046931740.1 → XP_046787696.1  tissue-type plasminogen activator isoform X3

  6. XM_046931741.1 → XP_046787697.1  tissue-type plasminogen activator isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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