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PDK1 pyruvate dehydrogenase kinase 1 [ Gallus gallus (chicken) ]

Gene ID: 425972, updated on 3-Apr-2024

Summary

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Symbol
PDK1provided by CGNC
Full Name
pyruvate dehydrogenase kinase 1provided by CGNC
Primary source
CGNC:52628
See related
Ensembl:ENSGALG00010021862
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (17321166..17332632, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (17239661..17251124, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor 4 Neighboring gene protein phosphatase 1 regulatory subunit 9 like Neighboring gene uncharacterized LOC101748000 Neighboring gene uncharacterized LOC121113411 Neighboring gene integrin subunit alpha 6 Neighboring gene distal-less homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PDK1 controls upstream PI3K expression and PIP3 generation. Dieterle AM, et al. Oncogene, 2014 Jun 5. PMID 23893244
  2. Analysis of chicken embryonic gonad expressed sequenced tags. Shin JH, et al. Anim Genet, 2006 Feb. PMID 16441308
  3. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article
  4. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate dehydrogenase kinase, isozyme 1
Names
pyruvate dehydrogenase kinase, isoenzyme 1
NP_001026523.2
XP_046777590.1
XP_046799651.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031352.4 → NP_001026523.2  pyruvate dehydrogenase kinase, isozyme 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000236
    UniProtKB/TrEMBL
    F1NLP2, Q5ZLT4
    Related
    ENSGALP00010032048.1, ENSGALT00010053188.1
    Conserved Domains (2) summary
    smart00387
    Location:242 → 362
    HATPase_c; Histidine kinase-like ATPases
    pfam10436
    Location:30 → 192
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    17321166..17332632 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046943695.1 → XP_046799651.1  pyruvate dehydrogenase kinase, isozyme 1 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    17239661..17251124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046921634.1 → XP_046777590.1  pyruvate dehydrogenase kinase, isozyme 1 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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