ESPL1 extra spindle pole bodies like 1, separase [Gallus gallus (chicken)] - Gene

Summary

Symbol: ESPL1provided by CGNC
Full Name: extra spindle pole bodies like 1, separaseprovided by CGNC
Primary source: CGNC:7565
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 34

Exon count:: 33

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	34	NC_052565.1 (1188010..1200187, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	34	NC_052606.1 (1147312..1159452, complement)

Chromosome 34 - NC_052565.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cysteine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in meiotic chromosome separation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitotic spindle	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: separin; LOW QUALITY PROTEIN: separin

Names: extra spindle pole bodies homolog 1

XP_040510871.2

EC 3.4.22.49

XP_040549933.1

EC 3.4.22.49

XP_040549934.1

EC 3.4.22.49

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052565.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1188010..1200187 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040654937.2 → XP_040510871.2 LOW QUALITY PROTEIN: separin isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052606.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

1147312..1159452 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040694000.2 → XP_040549934.1 separin isoform X3

Conserved Domains (2) summary

PHA03247
Location:1288 → 1497

PHA03247; large tegument protein UL36; Provisional

cl19248
Location:1794 → 2219

CHAT; CHAT domain
XM_040693999.2 → XP_040549933.1 separin isoform X2

Conserved Domains (2) summary

PHA03247
Location:1309 → 1518

PHA03247; large tegument protein UL36; Provisional

cl19248
Location:1815 → 2240

CHAT; CHAT domain