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PAK2 p21 (RAC1) activated kinase 2 [ Gallus gallus (chicken) ]

Gene ID: 424860, updated on 3-Apr-2024

Summary

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Symbol
PAK2provided by CGNC
Full Name
p21 (RAC1) activated kinase 2provided by CGNC
Primary source
CGNC:4842
See related
Ensembl:ENSGALG00010024742
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PAK2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
22
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (4295818..4333064, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (4128381..4165967, complement)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene galactose-3-O-sulfotransferase 4 Neighboring gene aquaporin 12A Neighboring gene phosphatidylinositol glycan anchor biosynthesis class X Neighboring gene centrosomal protein 19 Neighboring gene negative regulator of reactive oxygen species

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 2
Names
p21 (CDKN1A)-activated kinase 2
p21 protein (Cdc42/Rac)-activated kinase 2
XP_004937052.1
XP_025009521.1
XP_040534887.1
XP_040534888.1
XP_040534889.1
XP_040534890.1
XP_040534894.1
XP_040534895.1
XP_040561766.1
XP_040561769.1
XP_040561770.1
XP_046754499.1
XP_046754500.1
XP_046779993.1
XP_046779994.1
XP_422671.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4295818..4333064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025153753.3 → XP_025009521.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Related
    ENSGALP00010037158.1, ENSGALT00010060399.1
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  2. XM_422671.7 → XP_422671.2  serine/threonine-protein kinase PAK 2

    See identical proteins and their annotated locations for XP_422671.2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  3. XM_004936995.5 → XP_004937052.1  serine/threonine-protein kinase PAK 2

    See identical proteins and their annotated locations for XP_004937052.1

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Related
    ENSGALP00010037162.1, ENSGALT00010060403.1
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  4. XM_046898544.1 → XP_046754500.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    E1BS97

  5. XM_046898543.1 → XP_046754499.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    E1BS97

  6. XM_040705832.2 → XP_040561766.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  7. XM_040705835.2 → XP_040561769.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  8. XM_040705836.2 → XP_040561770.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4128381..4165967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040678955.2 → XP_040534889.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  2. XM_040678953.2 → XP_040534887.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  3. XM_040678954.2 → XP_040534888.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  4. XM_046924038.1 → XP_046779994.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    E1BS97

  5. XM_040678956.2 → XP_040534890.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  6. XM_040678960.2 → XP_040534894.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  7. XM_040678961.2 → XP_040534895.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    A0A8V0ZZL8, E1BS97
    Conserved Domains (2) summary
    cd06655
    Location:226 → 521
    STKc_PAK2; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 2
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  8. XM_046924037.1 → XP_046779993.1  serine/threonine-protein kinase PAK 2

    UniProtKB/TrEMBL
    E1BS97
Nucleotide Protein Strain
Heading Accession and Version

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