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HES6 hes family bHLH transcription factor 6 [ Gallus gallus (chicken) ]

Gene ID: 424829, updated on 19-Sep-2023

Summary

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Official Symbol
HES6provided by CGNC
Official Full Name
hes family bHLH transcription factor 6provided by CGNC
Primary source
CGNC:4117
See related
Ensembl:ENSGALG00010024997
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
cHes6-1; cHes6-2
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Genomic context

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Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (5123334..5125988)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (4929949..4932820)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417089 Neighboring gene lysophosphatidic acid receptor 6-like Neighboring gene integral membrane protein 2C Neighboring gene calcium binding protein 39 Neighboring gene translation initiation factor IF-2-like Neighboring gene microRNA 1577 Neighboring gene uncharacterized LOC121111482 Neighboring gene period circadian clock 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation. Vilas-Boas F, et al. PLoS One, 2010 Dec 2. PMID 21151987, Free PMC Article
  2. A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis. Fior R, et al. Dev Biol, 2005 May 15. PMID 15893982

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription cofactor HES-6
Names
hairy and enhancer of split 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394391.1 → NP_001381320.1  transcription cofactor HES-6

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V1A177, R4GJE7
    Related
    ENSGALP00010037767.1, ENSGALT00010061037.1
    Conserved Domains (2) summary
    cd11410
    Location:27 → 77
    bHLH_O_HES; basic helix-loop-helix-orange (bHLH-O) domain found in hairy and enhancer of split (HES) family
    pfam07527
    Location:92 → 130
    Hairy_orange; Hairy Orange

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5123334..5125988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040705892.2 → XP_040561826.1  transcription cofactor HES-6 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A177
    Conserved Domains (2) summary
    cd11410
    Location:27 → 76
    bHLH_O_HES; basic helix-loop-helix-orange (bHLH-O) domain found in hairy and enhancer of split (HES) family
    cl02638
    Location:89 → 124
    Hairy_orange; Hairy Orange

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4929949..4932820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040679071.2 → XP_040535005.1  transcription cofactor HES-6 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A177
    Conserved Domains (2) summary
    cd11410
    Location:27 → 76
    bHLH_O_HES; basic helix-loop-helix-orange (bHLH-O) domain found in hairy and enhancer of split (HES) family
    cl02638
    Location:89 → 124
    Hairy_orange; Hairy Orange
Nucleotide Protein Strain
Heading Accession and Version

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