HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: HMGCS2provided by CGNC
Full Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2provided by CGNC
Primary source: CGNC:2139
See related: Ensembl:ENSGALG00010013346
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	8	NC_052539.1 (4247895..4251997)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	8	NC_052580.1 (4259616..4263447)

Chromosome 8 - NC_052539.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hydroxymethylglutaryl-CoA synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in acetyl-CoA metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hydroxymethylglutaryl-CoA synthase, mitochondrial

Names: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)

XP_040533880.1

EC 2.3.3.10

XP_422225.6

EC 2.3.3.10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

4247895..4251997

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_422225.8 → XP_422225.6 hydroxymethylglutaryl-CoA synthase, mitochondrial

UniProtKB/TrEMBL

A0A8V0YDN2

Related

ENSGALP00010018918.1, ENSGALT00010032128.1

Conserved Domains (1) summary

TIGR01833
Location:43 → 500

HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

4259616..4263447

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040677946.2 → XP_040533880.1 hydroxymethylglutaryl-CoA synthase, mitochondrial

UniProtKB/TrEMBL

A0A8V0YDN2

Conserved Domains (1) summary

TIGR01833
Location:43 → 500

HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade