ERCC3 ERCC excision repair 3, TFIIH core complex helicase subunit [Gallus gallus (chicken)] - Gene

Summary

Symbol: ERCC3provided by CGNC
Full Name: ERCC excision repair 3, TFIIH core complex helicase subunitprovided by CGNC
Primary source: CGNC:8749
See related: Ensembl:ENSGALG00010021290
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	7	NC_052538.1 (23251347..23267922)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	7	NC_052579.1 (23170340..23186915)

Chromosome 7 - NC_052538.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 3'-5' DNA helicase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables hydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in nucleotide-excision repair	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of nucleotide-excision repair factor 3 complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription factor TFIIH holo complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription preinitiation complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: general transcription and DNA repair factor IIH helicase subunit XPB

Names: DNA excision repair protein ERCC-3; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH subunit XPB; excision repair cross-complementation group 3; excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

NP_001006523.2

EC 3.6.4.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006523.3 → NP_001006523.2 general transcription and DNA repair factor IIH helicase subunit XPB

Status: VALIDATED

Source sequence(s)

JAENSK010000236

UniProtKB/Swiss-Prot

Q5ZKK7

UniProtKB/TrEMBL

F1NZ23

Related

ENSGALP00010030779.1, ENSGALT00010051605.1

Conserved Domains (4) summary

TIGR00603
Location:57 → 777

rad25; DNA repair helicase rad25

pfam04851
Location:312 → 469

ResIII; Type III restriction enzyme, res subunit

pfam13625
Location:73 → 195

Helicase_C_3; Helicase conserved C-terminal domain

pfam16203
Location:493 → 734

ERCC3_RAD25_C; ERCC3/RAD25/XPB C-terminal helicase