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ITGA4 integrin subunit alpha 4 [ Gallus gallus (chicken) ]

Gene ID: 424121, updated on 5-Mar-2024

Summary

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Symbol
ITGA4provided by CGNC
Full Name
integrin subunit alpha 4provided by CGNC
Primary source
CGNC:6820
See related
Ensembl:ENSGALG00010026062
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ITGA4 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
28
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (13932489..13966234, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (13857230..13890964, complement)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene sperm specific antigen 2 Neighboring gene neuronal differentiation 1 Neighboring gene uncharacterized LOC107053809 Neighboring gene ceramide kinase like Neighboring gene uncharacterized LOC121113386 Neighboring gene ubiquitin conjugating enzyme E2 E3 Neighboring gene CWC22 spliceosome associated protein homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Integrin alpha4beta1 function is required for cell survival in developing retina. Leu ST, et al. Dev Biol, 2004 Dec 15. PMID 15581875
  2. The alpha4 subunit of integrin is important for neural crest cell migration. Kil SH, et al. Dev Biol, 1998 Oct 1. PMID 9758701

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-4
Names
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13932489..13966234 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_421974.8 → XP_421974.3  integrin alpha-4

    UniProtKB/TrEMBL
    A0A1D5PKL9, A0A8V1ACN1
    Related
    ENSGALP00010039230.1, ENSGALT00010063553.1
    Conserved Domains (3) summary
    smart00191
    Location:358 → 410
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:991 → 1005
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:455 → 892
    Integrin_alpha2; Integrin alpha

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13857230..13890964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040676057.2 → XP_040531991.1  integrin alpha-4

    UniProtKB/TrEMBL
    A0A1D5PKL9, A0A8V1ACN1
    Conserved Domains (3) summary
    smart00191
    Location:358 → 410
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam00357
    Location:991 → 1005
    Integrin_alpha; Integrin alpha cytoplasmic region
    pfam08441
    Location:455 → 892
    Integrin_alpha2; Integrin alpha
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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