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CASP10 caspase 10 [ Gallus gallus (chicken) ]

Gene ID: 424081, updated on 5-Mar-2024

Summary

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Symbol
CASP10provided by CGNC
Full Name
caspase 10provided by CGNC
Primary source
CGNC:6294
See related
Ensembl:ENSGALG00010024881
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human all
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Genomic context

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Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (11040333..11051864)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (10961367..10972902)

Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121113390 Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene CASP8 and FADD like apoptosis regulator Neighboring gene initiator caspase Neighboring gene caspase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caspase-10
Names
caspase 10, apoptosis-related cysteine peptidase
XP_004942667.2
XP_040532119.1
XP_040532120.1
XP_421936.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    11040333..11051864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004942610.5 → XP_004942667.2  caspase-10

    UniProtKB/TrEMBL
    A0A8V0ZVC6
    Conserved Domains (3) summary
    cd00032
    Location:283 → 526
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
    cd08814
    Location:101 → 181
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:7 → 88
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_421936.8 → XP_421936.5  caspase-10

    UniProtKB/TrEMBL
    A0A8V0ZVC6
    Related
    ENSGALP00010037507.1, ENSGALT00010060748.1
    Conserved Domains (3) summary
    cd00032
    Location:283 → 526
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
    cd08814
    Location:101 → 181
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:7 → 88
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10961367..10972902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040676186.2 → XP_040532120.1  caspase-10

    Conserved Domains (3) summary
    cd00032
    Location:283 → 526
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
    cd08814
    Location:101 → 181
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:7 → 88
    DD; Death Domain Superfamily of protein-protein interaction domains

  2. XM_040676185.2 → XP_040532119.1  caspase-10

    Conserved Domains (3) summary
    cd00032
    Location:283 → 526
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...
    cd08814
    Location:101 → 181
    DED_Caspase_10_r2; Death Effector Domain, repeat 2, of Caspase-10
    cl14633
    Location:7 → 88
    DD; Death Domain Superfamily of protein-protein interaction domains
Nucleotide Protein
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