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CASP7 caspase 7 [ Gallus gallus (chicken) ]

Gene ID: 423901, updated on 3-Apr-2024

Summary

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Symbol
CASP7provided by CGNC
Full Name
caspase 7provided by CGNC
Primary source
CGNC:6784
See related
Ensembl:ENSGALG00010019034
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CASP-7; Caspase-7
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (28295732..28316020)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (28186385..28206686)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418094 Neighboring gene hyaluronan binding protein 2 Neighboring gene nebulin-related anchoring protein Neighboring gene uncharacterized LOC112532669 Neighboring gene uncharacterized LOC121111209 Neighboring gene pleckstrin homology domain containing S1 Neighboring gene DNA cross-link repair 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. Korfali N, et al. J Biol Chem, 2004 Jan 9. PMID 14583630
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
caspase-7
Names
caspase 7, apoptosis-related cysteine peptidase
XP_025007610.1
XP_025007612.1
XP_025007614.1
XP_040530977.1
XP_040530978.1
XP_040530979.1
XP_040530980.1
XP_040530981.1
XP_040530982.1
XP_040530983.1
XP_040558934.1
XP_040558935.1
XP_040558936.1
XP_046776577.1
XP_046776578.1
XP_046799084.1
XP_046799085.1
XP_421764.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    28295732..28316020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040703001.2 → XP_040558935.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  2. XM_025151842.3 → XP_025007610.1  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61
    UniProtKB/TrEMBL
    A0A8V0Z940
    Related
    ENSGALP00010027471.1, ENSGALT00010046082.1
    Conserved Domains (1) summary
    cd00032
    Location:65 → 309
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  3. XM_025151846.3 → XP_025007614.1  caspase-7 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:61 → 305
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  4. XM_040703002.2 → XP_040558936.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  5. XM_046943128.1 → XP_046799084.1  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61

  6. XM_025151844.3 → XP_025007612.1  caspase-7 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:61 → 305
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  7. XM_040703000.2 → XP_040558934.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  8. XM_421764.7 → XP_421764.3  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61
    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:65 → 309
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  9. XM_046943129.1 → XP_046799085.1  caspase-7 isoform X3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    28186385..28206686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040675044.2 → XP_040530978.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  2. XM_040675047.2 → XP_040530981.1  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61
    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:65 → 309
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  3. XM_040675049.2 → XP_040530983.1  caspase-7 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:61 → 305
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  4. XM_040675045.2 → XP_040530979.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  5. XM_046920621.1 → XP_046776577.1  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61

  6. XM_040675048.2 → XP_040530982.1  caspase-7 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:61 → 305
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  7. XM_040675043.2 → XP_040530977.1  caspase-7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:66 → 310
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  8. XM_040675046.2 → XP_040530980.1  caspase-7 isoform X2

    UniProtKB/Swiss-Prot
    F1NV61
    UniProtKB/TrEMBL
    A0A8V0Z940
    Conserved Domains (1) summary
    cd00032
    Location:65 → 309
    CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...

  9. XM_046920622.1 → XP_046776578.1  caspase-7 isoform X3

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F1NV61.2 GenPept UniProtKB/Swiss-Prot:F1NV61

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