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MAPK8 mitogen-activated protein kinase 8 [ Gallus gallus (chicken) ]

Gene ID: 423778, updated on 3-Apr-2024

Summary

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Symbol
MAPK8provided by CGNC
Full Name
mitogen-activated protein kinase 8provided by CGNC
Primary source
CGNC:4584
See related
Ensembl:ENSGALG00010020460
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (18997558..19046413)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (18983760..19032559)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene FERM and PDZ domain containing 2 Neighboring gene FERM and PDZ domain-containing protein 2-like Neighboring gene Rho GTPase activating protein 22 Neighboring gene WDFY family member 4 Neighboring gene leucine rich repeat containing 18 Neighboring gene V-set and transmembrane domain containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MAPK8 regulates chicken male germ cell differentiation through JNK signaling pathway. Wang Y, et al. J Cell Biochem, 2018 Feb. PMID 28815778
  2. VEGF and RANKL regulation of NFATc1 in heart valve development. Combs MD, et al. Circ Res, 2009 Sep 11. PMID 19661463, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables JUN kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase 8
XP_001233169.1
XP_004942189.1
XP_004942190.1
XP_025007734.1
XP_040531328.1
XP_040531329.1
XP_040531330.1
XP_040531331.1
XP_040531332.1
XP_040531333.1
XP_040559100.1
XP_040559101.1
XP_046776789.1
XP_046776790.1
XP_046776791.1
XP_046776792.1
XP_046798934.1
XP_046798935.1
XP_046798936.1
XP_046798937.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18997558..19046413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040703166.1 → XP_040559100.1  mitogen-activated protein kinase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  2. XM_046942979.1 → XP_046798935.1  mitogen-activated protein kinase 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TY19

  3. XM_046942981.1 → XP_046798937.1  mitogen-activated protein kinase 8 isoform X3

    Related
    ENSGALP00010029251.1, ENSGALT00010049500.1

  4. XM_025151966.3 → XP_025007734.1  mitogen-activated protein kinase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  5. XM_004942132.5 → XP_004942189.1  mitogen-activated protein kinase 8 isoform X2

    See identical proteins and their annotated locations for XP_004942189.1

    UniProtKB/TrEMBL
    A0A3Q2TY19, A0A8V0ZDE6
    Related
    ENSGALP00010029248.1, ENSGALT00010049493.1
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  6. XM_004942133.5 → XP_004942190.1  mitogen-activated protein kinase 8 isoform X3

    See identical proteins and their annotated locations for XP_004942190.1

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Related
    ENSGALP00010029244.1, ENSGALT00010049485.1
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  7. XM_001233168.7 → XP_001233169.1  mitogen-activated protein kinase 8 isoform X1

    See identical proteins and their annotated locations for XP_001233169.1

    UniProtKB/TrEMBL
    A0A8V0Z7M5, A0A8V0ZDE6
    Related
    ENSGALP00010029249.1, ENSGALT00010049495.1
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  8. XM_040703167.2 → XP_040559101.1  mitogen-activated protein kinase 8 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZES8
    Related
    ENSGALP00010029237.1, ENSGALT00010049472.1
    Conserved Domains (1) summary
    cl21453
    Location:25 → 209
    PKc_like; Protein Kinases, catalytic domain

  9. XM_046942980.1 → XP_046798936.1  mitogen-activated protein kinase 8 isoform X3

  10. XM_046942978.1 → XP_046798934.1  mitogen-activated protein kinase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z7M5

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18983760..19032559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040675398.1 → XP_040531332.1  mitogen-activated protein kinase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  2. XM_046920834.1 → XP_046776790.1  mitogen-activated protein kinase 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TY19

  3. XM_046920836.1 → XP_046776792.1  mitogen-activated protein kinase 8 isoform X3

  4. XM_040675397.2 → XP_040531331.1  mitogen-activated protein kinase 8 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  5. XM_040675395.2 → XP_040531329.1  mitogen-activated protein kinase 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TY19, A0A8V0ZDE6
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  6. XM_040675396.2 → XP_040531330.1  mitogen-activated protein kinase 8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z7L9
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  7. XM_040675394.2 → XP_040531328.1  mitogen-activated protein kinase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z7M5, A0A8V0ZDE6
    Conserved Domains (1) summary
    cd07850
    Location:25 → 360
    STKc_JNK; Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase

  8. XM_040675399.2 → XP_040531333.1  mitogen-activated protein kinase 8 isoform X5

    UniProtKB/TrEMBL
    A0A8V0ZES8
    Conserved Domains (1) summary
    cl21453
    Location:25 → 209
    PKc_like; Protein Kinases, catalytic domain

  9. XM_046920835.1 → XP_046776791.1  mitogen-activated protein kinase 8 isoform X3

  10. XM_046920833.1 → XP_046776789.1  mitogen-activated protein kinase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z7M5
Nucleotide Protein Strain
Heading Accession and Version

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