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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001004405.3 → NP_001004405.2 calpain-3
Status: VALIDATED
- Source sequence(s)
-
JAENSK010000214
- UniProtKB/TrEMBL
- A0A1D5PLJ8, B8Y8S8
- Related
- ENSGALP00010027940.1, ENSGALT00010047044.1
- Conserved Domains (5) summary
-
- cd00051
Location:686 → 741
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam00648
Location:69 → 408
- Peptidase_C2; Calpain family cysteine protease
- pfam01067
Location:422 → 572
- Calpain_III; Calpain large subunit, domain III
- pfam13499
Location:717 → 773
- EF-hand_7; EF-hand domain pair
- pfam16648
Location:576 → 642
- Calpain_u2; Unstructured region on Calpain-3
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly
Genomic
-
NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly
- Range
-
25170021..25194170
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_015287074.4 → XP_015142560.1 calpain-3 isoform X1
- UniProtKB/TrEMBL
- A0A1L1RQ67, A0A8V0ZBA6
- Related
- ENSGALP00010027949.1, ENSGALT00010047063.1
- Conserved Domains (4) summary
-
- cd00051
Location:652 → 707
- EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
- pfam00648
Location:69 → 408
- Peptidase_C2; Calpain family cysteine protease
- pfam01067
Location:422 → 572
- Calpain_III; Calpain large subunit, domain III
- pfam13499
Location:683 → 739
- EF-hand_7; EF-hand domain pair
-
XM_040700950.1 → XP_040556884.1 calpain-3 isoform X2
- Conserved Domains (4) summary
-
- cd16190
Location:421 → 589
- EFh_PEF_CAPN3; Calcium-activated neutral
- pfam01067
Location:208 → 346
- Calpain_III; Calpain large subunit, domain III
- pfam16648
Location:355 → 421
- Calpain_u2; Unstructured region on Calpain-3
- cl00051
Location:1 → 187
- CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w
Genomic
-
NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w
- Range
-
25136629..25160769
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_046918428.1 → XP_046774384.1 calpain-3 isoform X1
-
XM_046918429.1 → XP_046774385.1 calpain-3 isoform X2