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CPT1A carnitine palmitoyltransferase 1A [ Gallus gallus (chicken) ]

Gene ID: 423118, updated on 3-Apr-2024

Summary

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Official Symbol
CPT1Aprovided by CGNC
Official Full Name
carnitine palmitoyltransferase 1Aprovided by CGNC
Primary source
CGNC:5344
See related
Ensembl:ENSGALG00010025905
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CPT1; L-CPT1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (16197964..16234089, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (16172235..16208376, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene testis expressed metallothionein like protein Neighboring gene uncharacterized LOC101751123 Neighboring gene galanin and GMAP prepropeptide Neighboring gene fatty acid desaturase 1-like Neighboring gene fatty acid desaturase 1-like Neighboring gene fatty acid desaturase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chicken liver and muscle carnitine palmitoyltransferase 1: nutritional regulation of messengers. Skiba-Cassy S, et al. Comp Biochem Physiol B Biochem Mol Biol, 2007 Jun. PMID 17337350
  2. Effect of chicken leptin recptor short hairpin RNA on expression of JAK2, STAT3, SOCS3 and CPT1 genes in chicken preadipocytes. Ban Q, et al. Anim Sci J, 2017 Mar. PMID 27868312
  3. Role of peroxisome proliferator-activated receptor alpha in the expression of hepatic fatty acid oxidation-related genes in chickens. Honda K, et al. Anim Sci J, 2016 Jan. PMID 26031853
  4. Effects of epigallocatechin gallate on lipid metabolism and its underlying molecular mechanism in broiler chickens. Huang JB, et al. J Anim Physiol Anim Nutr (Berl), 2015 Aug. PMID 25521589

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. It is associated with fatty acid metabolism.
    Title: Effect of chicken leptin recptor short hairpin RNA on expression of JAK2, STAT3, SOCS3 and CPT1 genes in chicken preadipocytes.
  2. It might play an important role in PPARalpha-induced fatty acid oxidation in the liver of chickens.
    Title: Role of peroxisome proliferator-activated receptor alpha in the expression of hepatic fatty acid oxidation-related genes in chickens.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carnitine O-palmitoyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carnitine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
carnitine O-palmitoyltransferase 1, liver isoform
Names
carnitine palmitoyltransferase 1A (liver)
carnitine palmitoyltransferase I
NP_001012916.1
XP_015142280.1
XP_015142283.1
XP_015142284.1
XP_040556811.1
XP_040556812.1
XP_040556813.1
XP_040556814.1
XP_040556815.1
XP_040556816.1
XP_046774234.1
XP_046774235.1
XP_046774236.1
XP_046774237.1
XP_046774238.1
XP_046774239.1
XP_046774240.1
XP_046774241.1
XP_046797599.1
XP_046797600.1
XP_046797601.1
XP_046797602.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012898.1 → NP_001012916.1  carnitine O-palmitoyltransferase 1, liver isoform

    See identical proteins and their annotated locations for NP_001012916.1

    Status: PROVISIONAL

    Source sequence(s)
    AY675193
    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    16197964..16234089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040700878.2 → XP_040556812.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

  2. XM_015286794.4 → XP_015142280.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Related
    ENSGALP00010038981.1, ENSGALT00010063148.1
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

  3. XM_015286798.4 → XP_015142284.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

    UniProtKB/TrEMBL
    A0A8V1ABZ2
    Conserved Domains (1) summary
    pfam00755
    Location:149 → 737
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

  4. XM_015286797.4 → XP_015142283.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

  5. XM_040700882.2 → XP_040556816.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

    UniProtKB/TrEMBL
    A0A8V1ABZ2
    Conserved Domains (1) summary
    pfam00755
    Location:149 → 737
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

  6. XM_040700877.2 → XP_040556811.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

  7. XM_040700880.2 → XP_040556814.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

    UniProtKB/TrEMBL
    A0A8V1ABZ2
    Conserved Domains (1) summary
    pfam00755
    Location:149 → 737
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

  8. XM_046941643.1 → XP_046797599.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  9. XM_046941646.1 → XP_046797602.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

  10. XM_040700879.2 → XP_040556813.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V1ABZ2, Q6B842
    Conserved Domains (2) summary
    pfam00755
    Location:171 → 759
    Carn_acyltransf; Choline/Carnitine o-acyltransferase
    pfam16484
    Location:1 → 47
    CPT_N; Carnitine O-palmitoyltransferase N-terminus

  11. XM_040700881.2 → XP_040556815.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

    UniProtKB/TrEMBL
    A0A8V1ABZ2
    Conserved Domains (1) summary
    pfam00755
    Location:149 → 737
    Carn_acyltransf; Choline/Carnitine o-acyltransferase

  12. XM_046941645.1 → XP_046797601.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  13. XM_046941644.1 → XP_046797600.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    16172235..16208376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046918280.1 → XP_046774236.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  2. XM_046918278.1 → XP_046774234.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  3. XM_046918285.1 → XP_046774241.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X2

  4. XM_046918281.1 → XP_046774237.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  5. XM_046918279.1 → XP_046774235.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  6. XM_046918283.1 → XP_046774239.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  7. XM_046918282.1 → XP_046774238.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842

  8. XM_046918284.1 → XP_046774240.1  carnitine O-palmitoyltransferase 1, liver isoform isoform X1

    UniProtKB/TrEMBL
    Q6B842
Nucleotide Protein Strain
Heading Accession and Version

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