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LRP5 LDL receptor related protein 5 [ Gallus gallus (chicken) ]

Gene ID: 423114, updated on 3-Apr-2024

Summary

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Symbol
LRP5provided by CGNC
Full Name
LDL receptor related protein 5provided by CGNC
Primary source
CGNC:51892
See related
Ensembl:ENSGALG00010025790
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (15926153..16060507)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (15900522..16034784)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene choline kinase alpha Neighboring gene lysine methyltransferase 5B Neighboring gene C11ORF24 homolog Neighboring gene uncharacterized LOC107053423 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene protein phosphatase 6 regulatory subunit 3 Neighboring gene testis expressed metallothionein like protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 5
Names
low density lipoprotein receptor-related protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012897.2 → NP_001012915.1  low-density lipoprotein receptor-related protein 5 precursor

    See identical proteins and their annotated locations for NP_001012915.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000214
    UniProtKB/TrEMBL
    A0A8V0ZZ36, Q5ZKF9
    Related
    ENSGALP00010038872.1, ENSGALT00010062938.1
    Conserved Domains (6) summary
    smart00135
    Location:407 → 449
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1299 → 1333
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:719 → 755
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:162 → 202
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam14670
    Location:298 → 335
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl18310
    Location:682 → 907
    NHL; NHL repeat unit of beta-propeller proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15926153..16060507
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040700872.2 → XP_040556806.1  low-density lipoprotein receptor-related protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZZ36, A0A8V0ZZ41
    Related
    ENSGALP00010038877.1, ENSGALT00010062944.1
    Conserved Domains (4) summary
    smart00135
    Location:385 → 427
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1277 → 1311
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:697 → 733
    NHL; NHL repeat [structural motif]
    cl18310
    Location:660 → 885
    NHL; NHL repeat unit of beta-propeller proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15900522..16034784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046918262.1 → XP_046774218.1  low-density lipoprotein receptor-related protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZZ41
Nucleotide Protein Strain
Heading Accession and Version

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