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F8 coagulation factor VIII [ Gallus gallus (chicken) ]

Gene ID: 422199, updated on 5-Mar-2024

Summary

Symbol
F8provided by CGNC
Full Name
coagulation factor VIIIprovided by CGNC
Primary source
CGNC:51654
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

Location:
chromosome: 4
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (2101058..2120537, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (2137552..2156961, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene membrane palmitoylated protein 1 Neighboring gene small integral membrane protein 9 Neighboring gene microRNA 222b Neighboring gene FUN14 domain containing 2 Neighboring gene C-X9-C motif containing 4

Genomic regions, transcripts, and products

Pathways from PubChem

General protein information

Preferred Names
coagulation factor VIII
Names
coagulation factor VIII, procoagulant component (hemophilia A)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2101058..2120537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_420193.8XP_420193.5  coagulation factor VIII

    UniProtKB/TrEMBL
    A0A1D5NW08
    Conserved Domains (5) summary
    smart00231
    Location:17971946
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    cd00057
    Location:18001945
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd04228
    Location:14741638
    CuRO_5_FVIII_like; The fifth cupredoxin domain of coagulation factor VIII and similar proteins
    cd11018
    Location:16501793
    CuRO_6_FVIII_like; The sixth cupredoxin domain of coagulation factor VIII and similar proteins
    cl19115
    Location:426602
    Cupredoxin; Cupredoxin superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2137552..2156961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040669502.2XP_040525436.1  coagulation factor VIII

    Conserved Domains (4) summary
    cd00057
    Location:18001945
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd04228
    Location:14741638
    CuRO_5_FVIII_like; The fifth cupredoxin domain of coagulation factor VIII and similar proteins
    cd11018
    Location:16501793
    CuRO_6_FVIII_like; The sixth cupredoxin domain of coagulation factor VIII and similar proteins
    cl19115
    Location:426602
    Cupredoxin; Cupredoxin superfamily