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PTK2B protein tyrosine kinase 2 beta [ Gallus gallus (chicken) ]

Gene ID: 421998, updated on 3-Apr-2024

Summary

Symbol
PTK2Bprovided by CGNC
Full Name
protein tyrosine kinase 2 betaprovided by CGNC
Primary source
CGNC:12407
See related
Ensembl:ENSGALG00010009972
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
34
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (104846159..104867946)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (104609826..104631578)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene GTPase, very large interferon inducible pseudogene 1 Neighboring gene selenoprotein I Neighboring gene uncharacterized LOC770271 Neighboring gene cholinergic receptor nicotinic alpha 2 subunit Neighboring gene uncharacterized LOC100857686

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in signal complex assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein-tyrosine kinase 2-beta
Names
PTK2B protein tyrosine kinase 2 beta
XP_015140708.3
XP_015140710.2
XP_015140711.2
XP_015140712.2
XP_040524276.1
XP_040524278.1
XP_040524279.1
XP_040524280.1
XP_040524283.1
XP_040554002.1
XP_040554005.1
XP_046770895.1
XP_046770896.1
XP_046770897.1
XP_046795359.1
XP_046795360.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    104846159..104867946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015285222.4XP_015140708.3  protein-tyrosine kinase 2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Related
    ENSGALP00010013595.1, ENSGALT00010023752.1
    Conserved Domains (3) summary
    cd05056
    Location:443712
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:65289
    B41; Band 4.1 homologues
    cd13190
    Location:285394
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  2. XM_040698071.2XP_040554005.1  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (3) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  3. XM_015285226.4XP_015140712.2  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (3) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  4. XM_046939404.1XP_046795360.1  protein-tyrosine kinase 2-beta isoform X3

  5. XM_015285224.4XP_015140710.2  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Related
    ENSGALP00010013594.1, ENSGALT00010023740.1
    Conserved Domains (3) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  6. XM_040698068.2XP_040554002.1  protein-tyrosine kinase 2-beta isoform X2

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (3) summary
    cd05056
    Location:443712
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:65289
    B41; Band 4.1 homologues
    cd13190
    Location:285394
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  7. XM_046939403.1XP_046795359.1  protein-tyrosine kinase 2-beta isoform X3

  8. XM_015285225.4XP_015140711.2  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Related
    ENSGALP00010013600.1, ENSGALT00010023766.1
    Conserved Domains (3) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    104609826..104631578
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040668342.2XP_040524276.1  protein-tyrosine kinase 2-beta isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (3) summary
    cd05056
    Location:443712
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:65289
    B41; Band 4.1 homologues
    cd13190
    Location:285394
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
  2. XM_040668349.2XP_040524283.1  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8821011
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:42140
    FERM_N_2; FERM N-terminal domain
  3. XM_040668344.2XP_040524278.1  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8821011
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:42140
    FERM_N_2; FERM N-terminal domain
  4. XM_046914941.1XP_046770897.1  protein-tyrosine kinase 2-beta isoform X3

  5. XM_040668345.2XP_040524279.1  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8821011
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:42140
    FERM_N_2; FERM N-terminal domain
  6. XM_046914940.1XP_046770896.1  protein-tyrosine kinase 2-beta isoform X3

  7. XM_046914939.1XP_046770895.1  protein-tyrosine kinase 2-beta isoform X3

  8. XM_040668346.2XP_040524280.1  protein-tyrosine kinase 2-beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0XZ77
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:44268
    B41; Band 4.1 homologues
    cd13190
    Location:264373
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:8821011
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:42140
    FERM_N_2; FERM N-terminal domain