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BMP6 bone morphogenetic protein 6 [ Gallus gallus (chicken) ]

Gene ID: 420868, updated on 5-Mar-2024

Summary

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Official Symbol
BMP6provided by CGNC
Official Full Name
bone morphogenetic protein 6provided by CGNC
Primary source
CGNC:9693
See related
Ensembl:ENSGALG00010010456
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (64111205..64197052, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (64059947..64145783, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene biogenesis of lysosomal organelles complex 1 subunit 5 Neighboring gene thioredoxin domain containing 5 Neighboring gene microRNA 6571 Neighboring gene desmoplakin Neighboring gene RIO kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The role of BMP6 in the proliferation and differentiation of chicken cartilage cells. Ye F, et al. PLoS One, 2019. PMID 31260450, Free PMC Article
  2. Bone morphogenetic protein 6 promotes FSH receptor and anti-Müllerian hormone mRNA expression in granulosa cells from hen prehierarchal follicles. Ocón-Grove OM, et al. Reproduction, 2012 Jun. PMID 22495888

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. data suggest that BMP6 may play a critical role in chicken cartilage cell proliferation and differentiation through the regulation of IGF1, JAK2, PKC, PTH, and IHH-PTHrP signaling pathways.
    Title: The role of BMP6 in the proliferation and differentiation of chicken cartilage cells.
  2. Bone morphogenetic protein 6 promotes FSH receptor and anti-Mullerian hormone mRNA expression in granulosa cells.
    Title: Bone morphogenetic protein 6 promotes FSH receptor and anti-Müllerian hormone mRNA expression in granulosa cells from hen prehierarchal follicles.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in SMAD protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bone morphogenetic protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    64111205..64197052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015275997.4 → XP_015131483.1  bone morphogenetic protein 6

    UniProtKB/TrEMBL
    A0A8V0Y5G9
    Related
    ENSGALP00010014197.1, ENSGALT00010024988.1
    Conserved Domains (2) summary
    cd19396
    Location:325 → 427
    TGF_beta_BMP6; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 6 (BMP-6) and similar proteins
    pfam00688
    Location:32 → 276
    TGFb_propeptide; TGF-beta propeptide

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    64059947..64145783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040664958.2 → XP_040520892.1  bone morphogenetic protein 6

    UniProtKB/TrEMBL
    A0A8V0Y5G9
    Conserved Domains (2) summary
    cd19396
    Location:325 → 427
    TGF_beta_BMP6; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 6 (BMP-6) and similar proteins
    pfam00688
    Location:32 → 276
    TGFb_propeptide; TGF-beta propeptide
Nucleotide Protein
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