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SFRP4 secreted frizzled related protein 4 [ Gallus gallus (chicken) ]

Gene ID: 420732, updated on 5-Mar-2024

Summary

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Symbol
SFRP4provided by CGNC
Full Name
secreted frizzled related protein 4provided by CGNC
Primary source
CGNC:9153
See related
Ensembl:ENSGALG00010016100
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (46070430..46080047)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (46117801..46127419)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109717 Neighboring gene ependymin related 1 Neighboring gene NME/NM23 family member 8 Neighboring gene uncharacterized LOC101748739 Neighboring gene uncharacterized LOC107052519

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    46070430..46080047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281688.4 → XP_015137174.2  secreted frizzled-related protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YUH4, A0A8V0YWH3
    Related
    ENSGALP00010022385.1, ENSGALT00010038704.1
    Conserved Domains (2) summary
    cd07442
    Location:50 → 176
    CRD_SFRP4; Cysteine-rich domain of the secreted frizzled-related protein 4 (SFRP4), a Wnt antagonist
    cd03581
    Location:223 → 331
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

  2. XM_015281689.4 → XP_015137175.2  secreted frizzled-related protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YUH4
    Related
    ENSGALP00010022384.1, ENSGALT00010038703.1
    Conserved Domains (2) summary
    cd07442
    Location:50 → 176
    CRD_SFRP4; Cysteine-rich domain of the secreted frizzled-related protein 4 (SFRP4), a Wnt antagonist
    cd03581
    Location:218 → 326
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    46117801..46127419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040664287.2 → XP_040520221.1  secreted frizzled-related protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YUH4
    Conserved Domains (2) summary
    cd07442
    Location:50 → 176
    CRD_SFRP4; Cysteine-rich domain of the secreted frizzled-related protein 4 (SFRP4), a Wnt antagonist
    cd03581
    Location:223 → 331
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...

  2. XM_040664288.2 → XP_040520222.1  secreted frizzled-related protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YUH4
    Conserved Domains (2) summary
    cd07442
    Location:50 → 176
    CRD_SFRP4; Cysteine-rich domain of the secreted frizzled-related protein 4 (SFRP4), a Wnt antagonist
    cd03581
    Location:218 → 326
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...
Nucleotide Protein
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