Sf3a1 Splicing factor 3a subunit 1 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Sf3a1provided by FlyBase
Official Full Name: Splicing factor 3a subunit 1provided by FlyBase
Primary source: FLYBASE:FBgn0266917
Locus tag: Dmel_CG16941
See related: AllianceGenome:FB:FBgn0266917
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG16941; Dmel\CG16941; l(2)SH3 146; l(3)SH146; sf3a1; SF3a1; SF3A1; SF3a120
Summary: Predicted to enable RNA binding activity. Involved in spermatogenesis. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in adult head; embryonic brain; embryonic/larval midgut; larval ventral nerve cord; and organism. Orthologous to human SF3A1 (splicing factor 3a subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (16999384..17002355, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (12825106..12828077, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in RNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA cis splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in mitotic cell cycle	HMP more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	HMP more info	PubMed
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of U2 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U2 snRNP	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of U2-type prespliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of catalytic step 2 spliceosome	HDA more info	PubMed
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IC Inferred by Curator more info	PubMed
part_of precatalytic spliceosome	HDA more info	PubMed

Names: CG16941-PA; Sf3a1-PA; lethal (3) SH146; splicing factor 3a, subunit 1

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The following sections contain reference sequences that belong to a specific genome build. Explain