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MAP3K3 mitogen-activated protein kinase kinase kinase 3 [ Gallus gallus (chicken) ]

Gene ID: 419954, updated on 5-Mar-2024

Summary

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Symbol
MAP3K3provided by CGNC
Full Name
mitogen-activated protein kinase kinase kinase 3provided by CGNC
Primary source
CGNC:323
See related
Ensembl:ENSGALG00010021605
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
1700012F10RIK
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (2376381..2415730)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (3594078..3633423)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily H member 6 Neighboring gene DDB1 and CUL4 associated factor 7 Neighboring gene uncharacterized LOC121107676 Neighboring gene LIM domain containing 2 Neighboring gene ring finger protein 113B Neighboring gene STE20-related kinase adaptor alpha

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Distribution and differential expression of microRNAs in the intestinal mucosal layer of necrotic enteritis induced Fayoumi chickens. Rengaraj D, et al. Asian-Australas J Anim Sci, 2017 Jul. PMID 28111433, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase 3
Names
WD-repeat protein
XP_040509184.1
XP_040509185.1
XP_040509186.1
XP_040547827.1
XP_040547828.1
XP_040547829.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2376381..2415730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040653252.2 → XP_040509186.1  mitogen-activated protein kinase kinase kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2U111
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cl21453
    Location:445 → 637
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040653250.2 → XP_040509184.1  mitogen-activated protein kinase kinase kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TZP2, A0A3Q2U111
    Related
    ENSGALP00010031355.1, ENSGALT00010052448.1
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:445 → 705
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  3. XM_040653251.2 → XP_040509185.1  mitogen-activated protein kinase kinase kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2U111
    Related
    ENSGALP00010031353.1, ENSGALT00010052446.1
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:387 → 647
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3594078..3633423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040691895.2 → XP_040547829.1  mitogen-activated protein kinase kinase kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2U111
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cl21453
    Location:445 → 637
    PKc_like; Protein Kinases, catalytic domain

  2. XM_040691893.2 → XP_040547827.1  mitogen-activated protein kinase kinase kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TZP2, A0A3Q2U111
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:445 → 705
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

  3. XM_040691894.2 → XP_040547828.1  mitogen-activated protein kinase kinase kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2U111
    Conserved Domains (2) summary
    cd06405
    Location:75 → 153
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    cd06625
    Location:387 → 647
    STKc_MEKK3_like; Catalytic domain of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases
Nucleotide Protein Strain
Heading Accession and Version

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