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MAD2L2 mitotic arrest deficient 2 like 2 [ Gallus gallus (chicken) ]

Gene ID: 419493, updated on 3-Apr-2024

Summary

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Official Symbol
MAD2L2provided by CGNC
Official Full Name
mitotic arrest deficient 2 like 2provided by CGNC
Primary source
CGNC:3434
See related
Ensembl:ENSGALG00010021207
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
REV7
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (5651054..5656779)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (5685153..5690888)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene chloride voltage-gated channel 6 Neighboring gene methylenetetrahydrofolate reductase Neighboring gene chromosome 1 open reading frame 167 Neighboring gene angiotensin II receptor associated protein Neighboring gene dorsal inhibitory axon guidance protein Neighboring gene F-box protein 44 Neighboring gene dispatched RND transporter family member 3 Neighboring gene uncharacterized LOC121107394 Neighboring gene guanylate cyclase activator 2B (uroguanylin)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Critical roles for polymerase zeta in cellular tolerance to nitric oxide-induced DNA damage. Wu X, et al. Cancer Res, 2006 Jan 15. PMID 16424005
  2. Multiple roles of vertebrate REV genes in DNA repair and recombination. Okada T, et al. Mol Cell Biol, 2005 Jul. PMID 15988022, Free PMC Article
  3. Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. Hara K, et al. J Biol Chem, 2010 Apr 16. PMID 20164194, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
part_of zeta DNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitotic spindle assembly checkpoint protein MAD2B
Names
MAD2 homolog
MAD2 mitotic arrest deficient-like 2
MAD2-like protein 2
mitotic arrest deficient 2-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025578.2 → NP_001020749.1  mitotic spindle assembly checkpoint protein MAD2B

    See identical proteins and their annotated locations for NP_001020749.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000329
    UniProtKB/Swiss-Prot
    Q4KWZ6
    UniProtKB/TrEMBL
    A0A8V0ZIG4
    Conserved Domains (1) summary
    pfam02301
    Location:18 → 103
    HORMA; HORMA domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5651054..5656779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903164.1 → XP_046759120.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  2. XM_040651194.2 → XP_040507128.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6
    UniProtKB/TrEMBL
    A0A8V0ZIG4
    Related
    ENSGALP00010030581.1, ENSGALT00010051390.1
    Conserved Domains (1) summary
    pfam02301
    Location:18 → 103
    HORMA; HORMA domain

  3. XM_046903163.1 → XP_046759119.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  4. XM_015296919.4 → XP_015152405.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6
    UniProtKB/TrEMBL
    A0A8V0ZIG4
    Conserved Domains (1) summary
    pfam02301
    Location:18 → 103
    HORMA; HORMA domain

RNA

  1. XR_005841378.2 RNA Sequence

  2. XR_005841377.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5685153..5690888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931334.1 → XP_046787290.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  2. XM_046931333.1 → XP_046787289.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  3. XM_046931331.1 → XP_046787287.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  4. XM_046931332.1 → XP_046787288.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

  5. XM_046931330.1 → XP_046787286.1  mitotic spindle assembly checkpoint protein MAD2B isoform X1

    UniProtKB/Swiss-Prot
    Q4KWZ6

RNA

  1. XR_006936858.1 RNA Sequence

  2. XR_006936859.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4KWZ6.1 GenPept UniProtKB/Swiss-Prot:Q4KWZ6

Gene LinkOut

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