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DHRS3 dehydrogenase/reductase 3 [ Gallus gallus (chicken) ]

Gene ID: 419480, updated on 3-Apr-2024

Summary

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Symbol
DHRS3provided by CGNC
Full Name
dehydrogenase/reductase 3provided by CGNC
Primary source
CGNC:3129
See related
Ensembl:ENSGALG00010021042 Ensembl:ENSGALG00010021075
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (5170653..5335439)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (5203901..5369479)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054938 Neighboring gene PR domain zinc finger protein 2-like Neighboring gene PR/SET domain 2 Neighboring gene uncharacterized LOC121107391 Neighboring gene podoplanin Neighboring gene uncharacterized LOC121107390 Neighboring gene chromosome 1 open reading frame 158 Neighboring gene arylacetamide deacetylase-like 3 Neighboring gene arylacetamide deacetylase like 3C Neighboring gene arylacetamide deacetylase like 3B Neighboring gene arylacetamide deacetylase like 3A Neighboring gene arylacetamide deacetylase like 4B Neighboring gene arylacetamide deacetylase like 4A Neighboring gene vacuolar protein sorting 13 homolog D Neighboring gene TNF receptor superfamily member 1B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated potassium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
short-chain dehydrogenase/reductase 3
Names
dehydrogenase/reductase (SDR family) member 3
NP_001264839.1
XP_004947554.1
XP_024998298.1
XP_024998300.2
XP_040507119.1
XP_040507120.1
XP_040507121.1
XP_040545180.1
XP_046759109.1
XP_046759110.1
XP_046759111.1
XP_046759112.1
XP_046759113.1
XP_046759114.1
XP_046759115.1
XP_046787264.1
XP_046787265.1
XP_046787266.1
XP_046787267.1
XP_046787268.1
XP_046787269.1
XP_046787270.1
XP_046787271.1
XP_046787272.1
XP_046787273.1
XP_046787274.1
XP_046787275.1
XP_046787276.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277910.4 → NP_001264839.1  short-chain dehydrogenase/reductase 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000329
    UniProtKB/TrEMBL
    A0A1D5P1J6
    Related
    ENSGALP00010030192.1, ENSGALT00010051001.1
    Conserved Domains (1) summary
    cd05339
    Location:41 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5170653..5335439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903153.1 → XP_046759109.1  short-chain dehydrogenase/reductase 3 isoform X1

  2. XM_040651185.2 → XP_040507119.1  short-chain dehydrogenase/reductase 3 isoform X1

    Conserved Domains (1) summary
    cd05339
    Location:41 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  3. XM_040651186.2 → XP_040507120.1  short-chain dehydrogenase/reductase 3 isoform X1

    Conserved Domains (1) summary
    cd05339
    Location:41 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  4. XM_025142530.3 → XP_024998298.1  short-chain dehydrogenase/reductase 3 isoform X1

    Conserved Domains (1) summary
    cd05339
    Location:41 → 281
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  5. XM_046903154.1 → XP_046759110.1  short-chain dehydrogenase/reductase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZGZ7
    Related
    ENSGALP00010030098.1, ENSGALT00010050907.1

  6. XM_046903155.1 → XP_046759111.1  short-chain dehydrogenase/reductase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZGZ7

  7. XM_046903156.1 → XP_046759112.1  short-chain dehydrogenase/reductase 3 isoform X5

  8. XM_004947497.5 → XP_004947554.1  short-chain dehydrogenase/reductase 3 isoform X2

    UniProtKB/TrEMBL
    F1P4Y4
    Related
    ENSGALP00010030100.1, ENSGALT00010050909.1
    Conserved Domains (3) summary
    COG4886
    Location:81 → 247
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:37 → 59
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 163
    LRR_8; Leucine rich repeat

  9. XM_040651187.2 → XP_040507121.1  short-chain dehydrogenase/reductase 3 isoform X6

    Conserved Domains (1) summary
    cd05339
    Location:2 → 197
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

  10. XM_046903157.1 → XP_046759113.1  short-chain dehydrogenase/reductase 3 isoform X6

  11. XM_046903159.1 → XP_046759115.1  short-chain dehydrogenase/reductase 3 isoform X6

  12. XM_046903158.1 → XP_046759114.1  short-chain dehydrogenase/reductase 3 isoform X6

  13. XM_025142532.3 → XP_024998300.2  short-chain dehydrogenase/reductase 3 isoform X3

    Conserved Domains (1) summary
    cd05339
    Location:54 → 269
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs

RNA

  1. XR_006931962.1 RNA Sequence

  2. XR_001469739.4 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5203901..5369479
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931310.1 → XP_046787266.1  short-chain dehydrogenase/reductase 3 isoform X1

  2. XM_046931308.1 → XP_046787264.1  short-chain dehydrogenase/reductase 3 isoform X1

  3. XM_046931309.1 → XP_046787265.1  short-chain dehydrogenase/reductase 3 isoform X1

  4. XM_046931311.1 → XP_046787267.1  short-chain dehydrogenase/reductase 3 isoform X1

  5. XM_046931313.1 → XP_046787269.1  short-chain dehydrogenase/reductase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZGZ7

  6. XM_046931314.1 → XP_046787270.1  short-chain dehydrogenase/reductase 3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZGZ7

  7. XM_046931315.1 → XP_046787271.1  short-chain dehydrogenase/reductase 3 isoform X5

  8. XM_040689246.2 → XP_040545180.1  short-chain dehydrogenase/reductase 3 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZFQ7, F1P4Y4
    Conserved Domains (3) summary
    COG4886
    Location:81 → 247
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:37 → 59
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 163
    LRR_8; Leucine rich repeat

  9. XM_046931316.1 → XP_046787272.1  short-chain dehydrogenase/reductase 3 isoform X6

  10. XM_046931317.1 → XP_046787273.1  short-chain dehydrogenase/reductase 3 isoform X6

  11. XM_046931320.1 → XP_046787276.1  short-chain dehydrogenase/reductase 3 isoform X6

  12. XM_046931318.1 → XP_046787274.1  short-chain dehydrogenase/reductase 3 isoform X6

  13. XM_046931319.1 → XP_046787275.1  short-chain dehydrogenase/reductase 3 isoform X6

  14. XM_046931312.1 → XP_046787268.1  short-chain dehydrogenase/reductase 3 isoform X3

RNA

  1. XR_006936856.1 RNA Sequence

  2. XR_006936857.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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