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PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Gallus gallus (chicken) ]

Gene ID: 419444, updated on 3-Apr-2024

Summary

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Symbol
PIK3CDprovided by CGNC
Full Name
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit deltaprovided by CGNC
Primary source
CGNC:1859
See related
Ensembl:ENSGALG00010017035
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (3443409..3489188)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (3476786..3522483)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 33 Neighboring gene transmembrane protein 201 Neighboring gene forkhead box protein D1 Neighboring gene calsyntenin 1 Neighboring gene uncharacterized LOC121107382 Neighboring gene catenin beta interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Names
phosphoinositide-3-kinase, catalytic, delta polypeptide
NP_001012714.2
XP_015152374.1
XP_024998287.1
XP_046787227.1
XP_046787228.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012696.2 → NP_001012714.2  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000329
    UniProtKB/TrEMBL
    F1NHX1, Q5F3P4
    Related
    ENSGALP00010024069.1, ENSGALT00010041133.1
    Conserved Domains (5) summary
    cd08693
    Location:315 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 687
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:679 → 1044
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:182 → 280
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    3443409..3489188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015296888.3 → XP_015152374.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F1NHX1, Q5F3P4
    Conserved Domains (5) summary
    cd08693
    Location:315 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 687
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:679 → 1044
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:182 → 280
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

  2. XM_025142519.3 → XP_024998287.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F1NHX1, Q5F3P4
    Conserved Domains (5) summary
    cd08693
    Location:315 → 481
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:504 → 687
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:679 → 1044
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:182 → 280
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:32 → 107
    PI3K_p85B; PI3-kinase family, p85-binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3476786..3522483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931271.1 → XP_046787227.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F1NHX1

  2. XM_046931272.1 → XP_046787228.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F1NHX1
Nucleotide Protein Strain
Heading Accession and Version

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