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DVL1 dishevelled segment polarity protein 1 [ Gallus gallus (chicken) ]

Gene ID: 419416, updated on 3-Apr-2024

Summary

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Symbol
DVL1provided by CGNC
Full Name
dishevelled segment polarity protein 1provided by CGNC
Primary source
CGNC:50995
See related
Ensembl:ENSGALG00010018012
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (2267329..2325025)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (2299283..2356979)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene aurora kinase A interacting protein 1 Neighboring gene matrix remodeling associated 8 Neighboring gene taste 1 receptor member 3 Neighboring gene lysophosphatidic acid receptor 6-like Neighboring gene integrator complex subunit 11 Neighboring gene ceramide-1-phosphate transfer protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome. Gignac SJ, et al. Dis Model Mech, 2023 Apr 1. PMID 36916233, Free PMC Article
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome.
    Title: Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
segment polarity protein dishevelled homolog DVL-1
Names
dishevelled, dsh homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2267329..2325025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015297118.4 → XP_015152604.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z4Q0, A0A8V0ZBP3
    Related
    ENSGALP00010025896.1, ENSGALT00010043543.1
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:418 → 501
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:505 → 702
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  2. XM_015297119.4 → XP_015152605.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z4Q0
    Related
    ENSGALP00010025889.1, ENSGALT00010043533.1
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:394 → 477
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:481 → 678
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  3. XM_015297120.4 → XP_015152606.1  segment polarity protein dishevelled homolog DVL-1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z476, A0A8V0ZBM6
    Related
    ENSGALP00010025881.1, ENSGALT00010043523.1
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:418 → 501
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:505 → 573
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  4. XM_046903222.1 → XP_046759178.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

  5. XM_046903223.1 → XP_046759179.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2299283..2356979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040689032.2 → XP_040544966.1  segment polarity protein dishevelled homolog DVL-1 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z4Q0, A0A8V0ZBP3
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:418 → 501
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:505 → 702
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  2. XM_040689033.2 → XP_040544967.1  segment polarity protein dishevelled homolog DVL-1 isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z4Q0
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:394 → 477
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:481 → 678
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  3. XM_040689034.2 → XP_040544968.1  segment polarity protein dishevelled homolog DVL-1 isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z476, A0A8V0ZBM6
    Conserved Domains (5) summary
    smart00021
    Location:1 → 85
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:252 → 339
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:418 → 501
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:90 → 250
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:505 → 573
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  4. XM_046931427.1 → XP_046787383.1  segment polarity protein dishevelled homolog DVL-1 isoform X3

  5. XM_046931428.1 → XP_046787384.1  segment polarity protein dishevelled homolog DVL-1 isoform X4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001030873.1: Suppressed sequence

    Description
    NM_001030873.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from rat: Dvl1 (GeneID:83721).
Nucleotide Protein Strain
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