U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRKCZ protein kinase C zeta [ Gallus gallus (chicken) ]

Gene ID: 419399, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Symbol
PRKCZprovided by CGNC
Full Name
protein kinase C zetaprovided by CGNC
Primary source
CGNC:866
See related
Ensembl:ENSGALG00010020059
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PRKCZ in Genome Data Viewer
Location:
chromosome: 21
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 21 NC_052552.1 (1792035..1832656, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 21 NC_052593.1 (1823503..1864113, complement)

Chromosome 21 - NC_052552.1Genomic Context describing neighboring genes Neighboring gene SKI proto-oncogene Neighboring gene microRNA 1635 Neighboring gene uncharacterized LOC107049018 Neighboring gene cilia and flagella associated protein 74 Neighboring gene gamma-aminobutyric acid type A receptor delta subunit Neighboring gene transmembrane protein 52

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Herrera A, et al. Nat Commun, 2014 Jun 19. PMID 24942669

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. beta-catenin controls the cell fate and polarity of the neuroblasts through the expression and localization of aPKC.
    Title: Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
protein kinase C zeta type
XP_004947451.1
XP_015152591.1
XP_024998399.1
XP_040507238.1
XP_040544978.1
XP_040544979.1
XP_040544980.1
XP_040544981.1
XP_040544982.1
XP_046759190.1
XP_046759191.1
XP_046759192.1
XP_046787395.1
XP_046787396.1
XP_046787397.1
XP_417561.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052552.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1792035..1832656 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903234.1 → XP_046759190.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    E1BQN6

  2. XM_015297105.4 → XP_015152591.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  3. XM_417561.8 → XP_417561.3  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Related
    ENSGALP00010028583.1, ENSGALT00010048475.1
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  4. XM_040651304.2 → XP_040507238.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Related
    ENSGALP00010028586.1, ENSGALT00010048482.1
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  5. XM_046903235.1 → XP_046759191.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    E1BQN6

  6. XM_025142631.3 → XP_024998399.1  protein kinase C zeta type isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z5Q9
    Conserved Domains (3) summary
    cd05617
    Location:163 → 519
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:56 → 110
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type
    cl02720
    Location:1 → 25
    PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...

  7. XM_046903236.1 → XP_046759192.1  protein kinase C zeta type isoform X4

  8. XM_004947394.5 → XP_004947451.1  protein kinase C zeta type isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z5Q9
    Conserved Domains (2) summary
    cd05617
    Location:135 → 491
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:28 → 82
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

RNA

  1. XR_005841406.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052593.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1823503..1864113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046931439.1 → XP_046787395.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    E1BQN6

  2. XM_040689046.2 → XP_040544980.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  3. XM_040689044.2 → XP_040544978.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  4. XM_040689045.2 → XP_040544979.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5Q9, E1BQN6
    Conserved Domains (3) summary
    cd06404
    Location:16 → 98
    PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...
    cd05617
    Location:236 → 592
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:129 → 183
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

  5. XM_046931440.1 → XP_046787396.1  protein kinase C zeta type isoform X1

    UniProtKB/TrEMBL
    E1BQN6

  6. XM_040689047.2 → XP_040544981.1  protein kinase C zeta type isoform X2

    UniProtKB/TrEMBL
    A0A8V0Z5Q9
    Conserved Domains (3) summary
    cd05617
    Location:163 → 519
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:56 → 110
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type
    cl02720
    Location:1 → 25
    PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...

  7. XM_046931441.1 → XP_046787397.1  protein kinase C zeta type isoform X4

  8. XM_040689048.2 → XP_040544982.1  protein kinase C zeta type isoform X3

    UniProtKB/TrEMBL
    A0A8V0Z5Q9
    Conserved Domains (2) summary
    cd05617
    Location:135 → 491
    STKc_aPKC_zeta; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C zeta
    cd21095
    Location:28 → 82
    C1_aPKC_zeta; protein kinase C conserved region 1 (C1 domain) found in the atypical protein kinase C (aPKC) zeta type

RNA

  1. XR_005855578.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.