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GNAS GNAS complex locus [ Gallus gallus (chicken) ]

Gene ID: 419313, updated on 5-Mar-2024

Summary

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Symbol
GNASprovided by CGNC
Full Name
GNAS complex locusprovided by CGNC
Primary source
CGNC:50967
See related
Ensembl:ENSGALG00010016384
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GNASXL; G-alpha-S
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (11257331..11388078, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (11044702..11175437, complement)

Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene microRNA 6597 Neighboring gene cathepsin Z Neighboring gene negative elongation factor complex member C/D Neighboring gene uncharacterized LOC121107349 Neighboring gene microRNA 6564 Neighboring gene aminopeptidase-like 1 Neighboring gene syntaxin 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Somitic disruption of GNAS in chick embryos mimics progressive osseous heteroplasia. Cairns DM, et al. J Clin Invest, 2013 Aug. PMID 23863715, Free PMC Article
  2. Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles. Eisenhardt AE, et al. Oncotarget, 2016 May 3. PMID 27034005, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D1 dopamine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G-protein beta/gamma-subunit complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-2 adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone receptor 1 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin-like growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ionotropic glutamate receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mu-type opioid receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating dopamine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide-binding protein G(s) subunit alpha
Names
guanine nucleotide-binding protein G(s) subunit alpha XL

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    11257331..11388078 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025142352.3 → XP_024998120.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TWD9
    Related
    ENSGALP00010022770.1, ENSGALT00010039463.1
    Conserved Domains (1) summary
    cd00066
    Location:79 → 411
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_046903073.1 → XP_046759029.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  3. XM_046903071.1 → XP_046759027.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  4. XM_025142353.3 → XP_024998121.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A1D5PDG4
    Related
    ENSGALP00010022767.1, ENSGALT00010039457.1
    Conserved Domains (1) summary
    cd00066
    Location:41 → 373
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  5. XM_046903070.1 → XP_046759026.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X5

  6. XM_025142355.3 → XP_024998123.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

    Conserved Domains (1) summary
    cd00066
    Location:1 → 314
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  7. XM_025142354.3 → XP_024998122.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A8V0YVI5
    Related
    ENSGALP00010022762.1, ENSGALT00010039451.1
    Conserved Domains (1) summary
    cd00066
    Location:17 → 343
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  8. XM_046903072.1 → XP_046759028.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  9. XM_040651033.2 → XP_040506967.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X6

    Conserved Domains (1) summary
    cd00066
    Location:1 → 168
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  10. XM_046903074.1 → XP_046759030.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X6

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    11044702..11175437 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040688340.2 → XP_040544274.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TWD9
    Conserved Domains (1) summary
    cd00066
    Location:79 → 411
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  2. XM_046931000.1 → XP_046786956.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  3. XM_046930998.1 → XP_046786954.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  4. XM_040688341.2 → XP_040544275.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A1D5PDG4
    Conserved Domains (1) summary
    cd00066
    Location:41 → 373
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  5. XM_046930997.1 → XP_046786953.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X5

  6. XM_040688343.2 → XP_040544277.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

    Conserved Domains (1) summary
    cd00066
    Location:1 → 314
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  7. XM_040688342.2 → XP_040544276.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A8V0YVI5
    Conserved Domains (1) summary
    cd00066
    Location:17 → 343
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  8. XM_046930999.1 → XP_046786955.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X4

  9. XM_040688344.2 → XP_040544278.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X6

    Conserved Domains (1) summary
    cd00066
    Location:1 → 168
    G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

  10. XM_046931001.1 → XP_046786957.1  guanine nucleotide-binding protein G(s) subunit alpha isoform X6

Nucleotide Protein Strain
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