U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ARHGEF7 Rho guanine nucleotide exchange factor 7 [ Gallus gallus (chicken) ]

Gene ID: 418761, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
ARHGEF7provided by CGNC
Official Full Name
Rho guanine nucleotide exchange factor 7provided by CGNC
Primary source
CGNC:12644
See related
Ensembl:ENSGALG00010013080
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
30
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (139315529..139423379)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (139314294..139422076)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109165 Neighboring gene ankyrin repeat domain 10 Neighboring gene uncharacterized LOC121107344 Neighboring gene uncharacterized LOC124417360 Neighboring gene SRY-box 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Characterization of the endogenous GIT1-betaPIX complex, and identification of its association to membranes. Botrugno OA, et al. Eur J Cell Biol, 2006 Jan. PMID 16373173

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
rho guanine nucleotide exchange factor 7
Names
Rho guanine nucleotide exchange factor (GEF) 7

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    139315529..139423379
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003640531.5 → XP_003640579.1  rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TZR1, A0A8V0YKD6
    Related
    ENSGALP00010018307.1, ENSGALT00010031379.1
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_004938542.5 → XP_004938599.1  rho guanine nucleotide exchange factor 7 isoform X3

    UniProtKB/TrEMBL
    A0A3Q3API9, A0A8V0YKD6
    Related
    ENSGALP00010018310.1, ENSGALT00010031382.1
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_025146726.3 → XP_025002494.1  rho guanine nucleotide exchange factor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YKD6
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 824
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_046903508.1 → XP_046759464.1  rho guanine nucleotide exchange factor 7 isoform X7

  5. XM_046903515.1 → XP_046759471.1  rho guanine nucleotide exchange factor 7 isoform X7

  6. XM_040651008.2 → XP_040506942.1  rho guanine nucleotide exchange factor 7 isoform X7

    UniProtKB/TrEMBL
    A0A8V0YKE6
    Conserved Domains (4) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

  7. XM_040651010.2 → XP_040506944.1  rho guanine nucleotide exchange factor 7 isoform X8

    UniProtKB/TrEMBL
    A0A8V0YKE6
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    cl27170
    Location:484 → 632
    DUF460; Protein of unknown function (DUF460)

  8. XM_046903533.1 → XP_046759489.1  rho guanine nucleotide exchange factor 7 isoform X9

  9. XM_046903522.1 → XP_046759478.1  rho guanine nucleotide exchange factor 7 isoform X7

  10. XM_040650999.2 → XP_040506933.1  rho guanine nucleotide exchange factor 7 isoform X4

    UniProtKB/TrEMBL
    A0A8V0YIC9, A0A8V0YQ66
    Related
    ENSGALP00010018297.1, ENSGALT00010031365.1
    Conserved Domains (4) summary
    cd12061
    Location:106 → 159
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:190 → 367
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:398 → 496
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:552 → 650
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

  11. XM_046903503.1 → XP_046759459.1  rho guanine nucleotide exchange factor 7 isoform X7

  12. XM_004938545.5 → XP_004938602.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YQ66
    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  13. XM_040651005.2 → XP_040506939.1  rho guanine nucleotide exchange factor 7 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YQ66
    Related
    ENSGALP00010018291.1, ENSGALT00010031359.1
    Conserved Domains (5) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    cl27170
    Location:559 → 707
    DUF460; Protein of unknown function (DUF460)

  14. XM_046903539.1 → XP_046759495.1  rho guanine nucleotide exchange factor 7 isoform X10

RNA

  1. XR_001464001.4 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    139314294..139422076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040658963.2 → XP_040514897.1  rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2TZR1, A0A8V0YKD6
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 859
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  2. XM_040658965.2 → XP_040514899.1  rho guanine nucleotide exchange factor 7 isoform X3

    UniProtKB/TrEMBL
    A0A3Q3API9, A0A8V0YKD6
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:714 → 800
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  3. XM_040658964.2 → XP_040514898.1  rho guanine nucleotide exchange factor 7 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YKD6
    Conserved Domains (7) summary
    cd12061
    Location:167 → 220
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:251 → 428
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:459 → 557
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:613 → 711
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:773 → 824
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:117 → 163
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cd21266
    Location:3 → 115
    CH_betaPIX; calponin homology (CH) domain found in beta-Pak Interactive eXchange factor

  4. XM_046909782.1 → XP_046765738.1  rho guanine nucleotide exchange factor 7 isoform X7

  5. XM_046909783.1 → XP_046765739.1  rho guanine nucleotide exchange factor 7 isoform X7

  6. XM_040658969.2 → XP_040514903.1  rho guanine nucleotide exchange factor 7 isoform X7

    UniProtKB/TrEMBL
    A0A8V0YKE6
    Conserved Domains (4) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

  7. XM_040658970.2 → XP_040514904.1  rho guanine nucleotide exchange factor 7 isoform X8

    UniProtKB/TrEMBL
    A0A8V0YKE6
    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    cl27170
    Location:484 → 632
    DUF460; Protein of unknown function (DUF460)

  8. XM_046909784.1 → XP_046765740.1  rho guanine nucleotide exchange factor 7 isoform X7

  9. XM_040658967.2 → XP_040514901.1  rho guanine nucleotide exchange factor 7 isoform X11

    UniProtKB/TrEMBL
    A0A8V0YQ66
    Conserved Domains (4) summary
    cd12061
    Location:84 → 137
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:168 → 345
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:376 → 474
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:530 → 628
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

  10. XM_046909781.1 → XP_046765737.1  rho guanine nucleotide exchange factor 7 isoform X7

  11. XM_040658966.2 → XP_040514900.1  rho guanine nucleotide exchange factor 7 isoform X5

    UniProtKB/TrEMBL
    A0A8V0YQ66
    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7
    cl00030
    Location:1 → 33
    CH_SF; calponin homology (CH) domain superfamily

  12. XM_040658968.2 → XP_040514902.1  rho guanine nucleotide exchange factor 7 isoform X6

    UniProtKB/TrEMBL
    A0A8V0YQ66
    Conserved Domains (5) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    cl27170
    Location:559 → 707
    DUF460; Protein of unknown function (DUF460)

  13. XM_046909785.1 → XP_046765741.1  rho guanine nucleotide exchange factor 7 isoform X10

RNA

  1. XR_005844265.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.