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GSK3A glycogen synthase kinase 3 alpha [ Gallus gallus (chicken) ]

Gene ID: 418335, updated on 3-Apr-2024

Summary

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Symbol
GSK3Aprovided by CGNC
Full Name
glycogen synthase kinase 3 alphaprovided by CGNC
Primary source
CGNC:11127
See related
Ensembl:ENSGALG00010025103
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GSK3B; GSK3beta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (80020837..80162885)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (80206355..80348494)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene microRNA 6609 Neighboring gene G protein-coupled receptor 156 Neighboring gene uncharacterized LOC121109314 Neighboring gene uncharacterized LOC107054682 Neighboring gene MYCBP associated and testis expressed 1 Neighboring gene uncharacterized LOC107054681

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cellular localization and signaling activity of beta-catenin in migrating neural crest cells. de Melker AA, et al. Dev Dyn, 2004 Aug. PMID 15254905
  2. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • AC006486.9

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables beta-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neuron projection development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of beta-catenin destruction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glycogen synthase kinase-3 beta
Names
GSK-3 betaserine/threonine-protein kinase GSK3B
glycogen synthase kinase 3 beta
XP_004938236.1
XP_040516343.1
XP_040516344.1
XP_040516345.1
XP_040563204.1
XP_046765879.1
XP_046769653.1
XP_416557.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    80020837..80162885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_416557.8 → XP_416557.4  glycogen synthase kinase-3 beta isoform X3

    See identical proteins and their annotated locations for XP_416557.4

    UniProtKB/TrEMBL
    A0A8V0ZWC4, A0A8V1A637
    Related
    ENSGALP00010037882.1, ENSGALT00010061259.1
    Conserved Domains (1) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  2. XM_004938179.5 → XP_004938236.1  glycogen synthase kinase-3 beta isoform X4

    See identical proteins and their annotated locations for XP_004938236.1

    UniProtKB/TrEMBL
    A0A8V0ZWC4
    Related
    ENSGALP00010037884.1, ENSGALT00010061264.1
    Conserved Domains (1) summary
    cd14137
    Location:51 → 343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  3. XM_046913697.1 → XP_046769653.1  glycogen synthase kinase-3 beta isoform X2

  4. XM_040707270.2 → XP_040563204.1  glycogen synthase kinase-3 beta isoform X1

    UniProtKB/TrEMBL
    F1NPL8
    Conserved Domains (1) summary
    cd14137
    Location:66 → 371
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    80206355..80348494
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040660410.2 → XP_040516344.1  glycogen synthase kinase-3 beta isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZWC4, A0A8V1A637
    Conserved Domains (1) summary
    cd14137
    Location:51 → 356
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  2. XM_040660411.2 → XP_040516345.1  glycogen synthase kinase-3 beta isoform X4

    UniProtKB/TrEMBL
    A0A8V0ZWC4
    Conserved Domains (1) summary
    cd14137
    Location:51 → 343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3

  3. XM_046909923.1 → XP_046765879.1  glycogen synthase kinase-3 beta isoform X2

  4. XM_040660409.2 → XP_040516343.1  glycogen synthase kinase-3 beta isoform X1

    UniProtKB/TrEMBL
    F1NPL8
    Conserved Domains (1) summary
    cd14137
    Location:66 → 371
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
Nucleotide Protein
Heading Accession and Version

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