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ZYX zyxin [ Gallus gallus (chicken) ]

Gene ID: 418300, updated on 3-Apr-2024

Summary

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Symbol
ZYXprovided by CGNC
Full Name
zyxinprovided by CGNC
Primary source
CGNC:10889
See related
Ensembl:ENSGALG00010023926
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (77483646..77495180, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (77684571..77696074, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene putative olfactory receptor 10AC1-like Neighboring gene EPH receptor A1 Neighboring gene uncharacterized LOC107054541 Neighboring gene family with sequence similarity 131 member B Neighboring gene uncharacterized LOC124417615 Neighboring gene chloride voltage-gated channel 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Zyxin regulates cell migration and differentiation in EMT during chicken AV valve morphogenesis. Li N, et al. Microsc Microanal, 2013 Aug. PMID 23742986
  2. Association of resistance to avian coccidiosis with single nucleotide polymorphisms in the zyxin gene. Hong YH, et al. Poult Sci, 2009 Mar. PMID 19211519
  3. Characterisation of chicken TES and its role in cell spreading and motility. Griffith E, et al. Cell Motil Cytoskeleton, 2004 Mar. PMID 14743347
  4. Biochemical and molecular characterization of the chicken cysteine-rich protein, a developmentally regulated LIM-domain protein that is associated with the actin cytoskeleton. Crawford AW, et al. J Cell Biol, 1994 Jan. PMID 8294495, Free PMC Article
  5. An interaction between zyxin and alpha-actinin. Crawford AW, et al. J Cell Biol, 1992 Mar. PMID 1541635, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Thus, zyxin appears to play a role as a regulator of cell migration and differentiation during epithelial-mesenchymal transformation in chicken atrioventricular valve formation.
    Title: Zyxin regulates cell migration and differentiation in EMT during chicken AV valve morphogenesis.
  2. The roles of multiple haplotypes of zyxin with resistance to experimental avian coccidiosis are reported.
    Title: Association of resistance to avian coccidiosis with single nucleotide polymorphisms in the zyxin gene.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
zyxin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004386.2 → NP_001004386.1  zyxin

    See identical proteins and their annotated locations for NP_001004386.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000015
    UniProtKB/Swiss-Prot
    Q04584
    UniProtKB/TrEMBL
    A0A8V1A2E5
    Related
    ENSGALP00010035409.1, ENSGALT00010058285.1
    Conserved Domains (4) summary
    cd09349
    Location:319 → 405
    LIM1_Zyxin; The first LIM domain of Zyxin
    cd09353
    Location:412 → 471
    LIM2_Zyxin; The second LIM domain of Zyxin
    cd09435
    Location:472 → 538
    LIM3_Zyxin; The third LIM domain of Zyxin
    PHA03247
    Location:136 → 318
    PHA03247; large tegument protein UL36; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    77483646..77495180 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015293446.4 → XP_015148932.1  zyxin isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZWZ1
    Conserved Domains (3) summary
    cd09349
    Location:350 → 436
    LIM1_Zyxin; The first LIM domain of Zyxin
    cd09353
    Location:443 → 502
    LIM2_Zyxin; The second LIM domain of Zyxin
    cd09435
    Location:503 → 569
    LIM3_Zyxin; The third LIM domain of Zyxin

  2. XM_046939743.1 → XP_046795699.1  zyxin isoform X3

  3. XM_046939727.1 → XP_046795683.1  zyxin isoform X1

  4. XM_046939740.1 → XP_046795696.1  zyxin isoform X2

  5. XM_015293439.4 → XP_015148925.1  zyxin isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZWZ1
    Related
    ENSGALP00010035404.1, ENSGALT00010058279.1
    Conserved Domains (3) summary
    cd09349
    Location:350 → 436
    LIM1_Zyxin; The first LIM domain of Zyxin
    cd09353
    Location:443 → 502
    LIM2_Zyxin; The second LIM domain of Zyxin
    cd09435
    Location:503 → 569
    LIM3_Zyxin; The third LIM domain of Zyxin

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    77684571..77696074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907752.1 → XP_046763708.1  zyxin isoform X2

  2. XM_046907754.1 → XP_046763710.1  zyxin isoform X3

  3. XM_046907751.1 → XP_046763707.1  zyxin isoform X1

  4. XM_046907753.1 → XP_046763709.1  zyxin isoform X2

  5. XM_046907755.1 → XP_046763711.1  zyxin isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04584.1 GenPept UniProtKB/Swiss-Prot:Q04584

Gene LinkOut

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Molecular Biology Databases
Research Materials
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