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KRAS KRAS proto-oncogene, GTPase [ Gallus gallus (chicken) ]

Gene ID: 418207, updated on 3-Apr-2024

Summary

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Symbol
KRASprovided by CGNC
Full Name
KRAS proto-oncogene, GTPaseprovided by CGNC
Primary source
CGNC:10484
See related
Ensembl:ENSGALG00010014246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (67266767..67288578, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (67565478..67590480, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-triphosphate receptor associated 2 Neighboring gene microRNA 7451 Neighboring gene dynein axonemal intermediate chain 7 Neighboring gene uncharacterized LOC121109058 Neighboring gene electron transfer flavoprotein regulatory factor 1 Neighboring gene uncharacterized LOC121109059 Neighboring gene uncharacterized LOC107054089 Neighboring gene uncharacterized LOC121109060

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTPase KRas
Names
Kirsten rat sarcoma viral oncogene homolog
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
NP_001243091.1
XP_015145733.1
XP_015145740.1
XP_015145751.1
XP_015145758.1
XP_040553252.1
XP_046763601.1
XP_046763602.1
XP_046763603.1
XP_046763604.1
XP_046763605.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256162.1 → NP_001243091.1  GTPase KRas

    See identical proteins and their annotated locations for NP_001243091.1

    Status: VALIDATED

    Source sequence(s)
    HQ439437, JAENSK010000012
    UniProtKB/TrEMBL
    A0A1D5NY37, F5ANT2
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    67266767..67288578 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015290265.4 → XP_015145751.1  GTPase KRas isoform X3

    UniProtKB/TrEMBL
    A0A1D5NY37, F5ANT2
    Related
    ENSGALP00010020154.1, ENSGALT00010034306.1
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  2. XM_015290272.4 → XP_015145758.1  GTPase KRas isoform X2

    UniProtKB/TrEMBL
    F5ANT2
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  3. XM_040697318.2 → XP_040553252.1  GTPase KRas isoform X3

    UniProtKB/TrEMBL
    A0A1D5NY37, F5ANT2
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  4. XM_015290247.4 → XP_015145733.1  GTPase KRas isoform X1

    UniProtKB/TrEMBL
    A0A1D5PT95
    Related
    ENSGALP00010020151.1, ENSGALT00010034301.1
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  5. XM_015290254.4 → XP_015145740.1  GTPase KRas isoform X1

    UniProtKB/TrEMBL
    A0A1D5PT95
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    67565478..67590480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907645.1 → XP_046763601.1  GTPase KRas isoform X4

  2. XM_046907649.1 → XP_046763605.1  GTPase KRas isoform X2

  3. XM_046907646.1 → XP_046763602.1  GTPase KRas isoform X1

    UniProtKB/TrEMBL
    A0A1D5PT95

  4. XM_046907647.1 → XP_046763603.1  GTPase KRas isoform X1

    UniProtKB/TrEMBL
    A0A1D5PT95

  5. XM_046907648.1 → XP_046763604.1  GTPase KRas isoform X5

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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