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APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [ Gallus gallus (chicken) ]

Gene ID: 418075, updated on 5-Mar-2024

Summary

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Official Symbol
APPL2provided by CGNC
Official Full Name
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2provided by CGNC
Primary source
CGNC:9611
See related
Ensembl:ENSGALG00010011605
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (54258352..54291814)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (54549326..54582791)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107053559 Neighboring gene chromosome 12 open reading frame 75 Neighboring gene uncharacterized LOC121107117 Neighboring gene microRNA mir-12210 Neighboring gene WASH complex subunit 4 Neighboring gene uncharacterized LOC121107114 Neighboring gene aldehyde dehydrogenase 1 family member L2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DCC-interacting protein 13-beta
Names
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    54258352..54291814
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003640409.6 → XP_003640457.1  DCC-interacting protein 13-beta

    See identical proteins and their annotated locations for XP_003640457.1

    UniProtKB/TrEMBL
    A0A8V0YBR8, A0A8V0YIP0
    Related
    ENSGALP00010015913.1, ENSGALT00010027763.1
    Conserved Domains (3) summary
    cd07632
    Location:20 → 234
    BAR_APPL2; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 2
    cd13158
    Location:478 → 611
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    54549326..54582791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040658795.2 → XP_040514729.1  DCC-interacting protein 13-beta

    UniProtKB/TrEMBL
    A0A8V0YBR8, A0A8V0YIP0
    Conserved Domains (3) summary
    cd07632
    Location:20 → 234
    BAR_APPL2; The Bin/Amphiphysin/Rvs (BAR) domain of Adaptor protein, Phosphotyrosine interaction, PH domain and Leucine zipper containing 2
    cd13158
    Location:478 → 611
    PTB_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif (APPL; also called DCC-interacting protein (DIP)-13alpha) Phosphotyrosine-binding (PTB) domain
    cd13247
    Location:252 → 376
    BAR-PH_APPL; Adaptor protein containing PH domain, PTB domain, and Leucine zipper motif Bin1/amphiphysin/Rvs167 (BAR)-Pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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