WASL Wiskott-Aldrich syndrome like [Gallus gallus (chicken)] - Gene

Summary

Symbol: WASLprovided by CGNC
Full Name: Wiskott-Aldrich syndrome likeprovided by CGNC
Primary source: CGNC:6677
See related: Ensembl:ENSGALG00010001686
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (22376967..22426924)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (22631610..22681685)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables microtubule binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament organization	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: actin nucleation-promoting factor WASL; neural Wiskott-Aldrich syndrome protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199500.3 → NP_001186429.2 actin nucleation-promoting factor WASL

Status: VALIDATED

Source sequence(s)

JAENSK010000012

UniProtKB/TrEMBL

A0A8V0XCI1, E1BTH9

Related

ENSGALP00010002173.1, ENSGALT00010003869.1

Conserved Domains (4) summary

smart00246
Location:433 → 450

WH2; Wiskott Aldrich syndrome homology region 2

cd01205
Location:40 → 138

EVH1_WASP-like; WASP family proteins EVH1 domain

pfam00786
Location:202 → 258

PBD; P21-Rho-binding domain

pfam02205
Location:402 → 425

WH2; WH2 motif

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

22376967..22426924

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025147539.3 → XP_025003307.1 neural Wiskott-Aldrich syndrome protein isoform X1

UniProtKB/TrEMBL

A0A8V0X6F7, A0A8V0XCI1

Related

ENSGALP00010002172.1, ENSGALT00010003868.1

Conserved Domains (4) summary

smart00246
Location:439 → 456

WH2; Wiskott Aldrich syndrome homology region 2

cd01205
Location:40 → 138

EVH1_WASP-like; WASP family proteins EVH1 domain

pfam00786
Location:202 → 259

PBD; P21-Rho-binding domain

pfam02205
Location:408 → 431

WH2; WH2 motif