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PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Gallus gallus (chicken) ]

Gene ID: 417706, updated on 3-Apr-2024

Summary

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Symbol
PIK3CGprovided by CGNC
Full Name
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammaprovided by CGNC
Primary source
CGNC:6119
See related
Ensembl:ENSGALG00010009050
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (14594616..14629783)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (14732122..14767291)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417288 Neighboring gene coiled-coil domain containing 71-like Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta Neighboring gene HMG-box transcription factor 1 Neighboring gene component of oligomeric golgi complex 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia. Huang Y, et al. Invest Ophthalmol Vis Sci, 2019 Feb 1. PMID 30721303, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IA IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class IB IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Names
phosphoinositide-3-kinase, catalytic, gamma polypeptide
NP_001186467.1
XP_015131201.1
XP_046763009.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199538.3 → NP_001186467.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/TrEMBL
    A0A8V0XZY7, E1C093
    Related
    ENSGALP00010012303.1, ENSGALT00010021598.1
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14594616..14629783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015275715.4 → XP_015131201.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

    UniProtKB/TrEMBL
    A0A8V0XZY7, E1C093
    Conserved Domains (4) summary
    cd08399
    Location:350 → 530
    C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:552 → 728
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd00894
    Location:732 → 1098
    PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
    cl02484
    Location:203 → 312
    PI3K_rbd; PI3-kinase family, ras-binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    14732122..14767291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907053.1 → XP_046763009.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

    UniProtKB/TrEMBL
    E1C093
Nucleotide Protein
Heading Accession and Version

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